Human brucellosis

MP Franco, M Mulder, RH Gilman… - The Lancet infectious …, 2007 - thelancet.com
Human brucellosis still presents scientists and clinicians with several challenges, such as
the understanding of pathogenic mechanisms of Brucella spp, the identification of markers …

Brucellosis: a worldwide zoonosis

ML Boschiroli, V Foulongne, D O'Callaghan - Current opinion in …, 2001 - Elsevier
Brucella is one of the world's major zoonotic pathogens, and is responsible for enormous
economic losses as well as considerable human morbidity in endemic areas. Control of …

Brucella Evades Macrophage Killing via VirB-dependent Sustained Interactions with the Endoplasmic Reticulum

J Celli, C de Chastellier, DM Franchini… - The Journal of …, 2003 - rupress.org
The intracellular pathogen Brucella is the causative agent of brucellosis, a worldwide
zoonosis that affects mammals, including humans. Essential to Brucella virulence is its …

Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans

J Ko, GA Splitter - Clinical microbiology reviews, 2003 - Am Soc Microbiol
Brucellosis caused by Brucella spp. is a major zoonotic disease. Control of brucellosis in
agricultural animals is a prerequisite for the prevention of this disease in human beings …

The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts

IT Paulsen, R Seshadri, KE Nelson… - Proceedings of the …, 2002 - National Acad Sciences
The 3.31-Mb genome sequence of the intracellular pathogen and potential bioterrorism
agent, Brucella suis, was determined. Comparison of B. suis with Brucella melitensis has …

The Intracellular Life Cycle of Brucella spp

J Celli - Microbiology spectrum, 2019 - Am Soc Microbiol
Bacteria of the genus Brucella colonize a wide variety of mammalian hosts, in which their
infectious cycle and ability to cause disease predominantly rely on an intracellular lifestyle …

Brucella Intracellular Replication Requires Trafficking Through the Late Endosomal/Lysosomal Compartment

T Starr, TW Ng, TD Wehrly, LA Knodler, J Celli - Traffic, 2008 - Wiley Online Library
Upon entry into mammalian cells, the intracellular pathogen Brucella abortus resides within
a membrane‐bound compartment, the Brucella‐containing vacuole (BCV), the maturation of …

Invasion of the central nervous system by intracellular bacteria

DA Drevets, PJM Leenen… - Clinical microbiology …, 2004 - Am Soc Microbiol
Infection of the central nervous system (CNS) is a severe and frequently fatal event during
the course of many diseases caused by microbes with predominantly intracellular life cycles …

Brucellosis: review on the recent trends in pathogenicity and laboratory diagnosis

S Christopher - Journal of laboratory physicians, 2010 - thieme-connect.com
Brucellosis is a zoonotic infection transmitted from animals to humans by the ingestion of
infected food products, direct contact with an infected animal or inhalation of aerosols. The …

Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host

RM Roop, JM Gaines, ES Anderson… - Medical microbiology …, 2009 - Springer
Brucella strains produce abortion and infertility in their natural hosts and a zoonotic disease
in humans known as undulant fever. These bacteria do not produce classical virulence …