Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …

Renal tissue injury initiates inflammatory and fibrotic processes that occur to promote
regeneration and repair. After renal injury, damaged tissue releases cytokines and …

The association between proton pump inhibitors (PPI) use and risk of acute interstitial
nephritis has been described. However, whether exposure to PPI associates with incident …

Acute kidney injury is a clinical syndrome characterized by a rapid decline in glomerular
filtration rate and resultant accumulation of metabolic waste products. Acute kidney injury is …

Symptoms) is a complex multisystemic severe drug hypersensitivity reaction whose
diagnosis and management are troublesome. It involves the management by different …

Proton pump inhibitor (PPI) use is associated with an increased risk of acute kidney injury
(AKI), incident chronic kidney disease (CKD), and progression to end-stage renal disease …

Background Proton pump inhibitors (PPIs) cause interstitial nephritis and are an
underappreciated cause of acute kidney injury. We examined the risk of acute kidney injury …

The kidney plays a primary role in maintaining homeostasis and detoxification of numerous
hydrophilic xenobiotics as well as endogenous compounds. Because the kidney is exposed …

Background Existing epidemiological studies illustrate that proton pump inhibitors (PPIs)
may be related to adverse kidney outcomes. To date, no comprehensive meta-analysis has …

Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of
nonkidney adverse health outcomes and several untoward kidney outcomes, including …