[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

Preeclampsia: updates in pathogenesis, definitions, and guidelines

E Phipps, D Prasanna, W Brima… - Clinical Journal of the …, 2016 - journals.lww.com
Preeclampsia is becoming an increasingly common diagnosis in the developed world and
remains a high cause of maternal and fetal morbidity and mortality in the developing world …

Preeclampsia: Pathophysiology and management

R Nirupama, S Divyashree, P Janhavi… - Journal of gynecology …, 2021 - Elsevier
Preeclampsia is a pregnancy-related multisystem disorder, frequently encountered
pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset …

Placental adaptation: what can we learn from birthweight: placental weight ratio?

CE Hayward, S Lean, CP Sibley, RL Jones… - Frontiers in …, 2016 - frontiersin.org
Appropriate fetal growth relies upon adequate placental nutrient transfer. Birthweight:
placental weight ratio (BW: PW ratio) is often used as a proxy for placental efficiency, defined …

Regulation of placental angiogenesis

D Chen, J Zheng - Microcirculation, 2014 - Wiley Online Library
Ample interest has been evoked in using placental angiogenesis as a target for the
development of diagnosis tools and potential therapeutics for pregnancy complications …

Hypoxia and placental development

MJ Soares, K Iqbal, K Kozai - Birth defects research, 2017 - Wiley Online Library
Hemochorial placentation is orchestrated through highly regulated temporal and spatial
decisions governing the fate of trophoblast stem/progenitor cells. Trophoblast cell …

Environmental exposures and congenital heart disease

R Boyd, H McMullen, H Beqaj, D Kalfa - Pediatrics, 2022 - publications.aap.org
Congenital heart disease (CHD) is the most common congenital abnormality worldwide,
affecting 8 to 12 infants per 1000 births globally and causing> 40% of prenatal deaths …

Placental bed research: II. Functional and immunological investigations of the placental bed

LK Harris, M Benagiano, MM D'elios, I Brosens… - American journal of …, 2019 - Elsevier
Research on the placenta as the interface between the mother and the fetus has been
undertaken for some 150 years, and in 2 subsequent reviews, we attempted to summarize …

Animal models of preeclampsia: causes, consequences, and interventions

KL Gatford, PH Andraweera, CT Roberts, AS Care - Hypertension, 2020 - Am Heart Assoc
Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia

SD Burke, ZK Zsengellér, EV Khankin… - The Journal of …, 2016 - Am Soc Clin Investig
Preeclampsia is a hypertensive disorder of pregnancy in which patients develop profound
sensitivity to vasopressors, such as angiotensin II, and is associated with substantial …