Colorectal cancer is one of the major causes of cancer‐related death in the Western world.
Patient survival is highly dependent on the tumor stage at the time of diagnosis. Reduced …

Background Identifying risk factors for metachronous colorectal cancer (CRC) and
metachronous advanced neoplasia could be useful for guiding surveillance. We conducted …

Curcumin (diferuloylmethane), which has been shown to inhibit growth of transformed cells,
has no discernible toxicity and achieves high levels in colonic mucosa. 5‐fluorouracil (5‐FU) …

Defects in the mismatch repair (MMR) genes hMLH1 and hMSH2 have been found in 10%
to 20% of sporadic colorectal carcinomas and also many cases of hereditary nonpolyposis …

Background & Aims: Methylation of the hMLH1 promoter region is frequently observed in
microsatellite instability (MSI)-positive sporadic colorectal carcinomas. We studied hMLH1 …

Despite the use of surgical resection and aggressive chemotherapy, nearly 50% of patients
with colorectal carcinoma develop recurrent disease, highlighting the need for improved …

AIM: To investigate the clinical features, diagnosis, treatment and prognosis of multiple
primary colorectal carcinomas (MPCC). METHODS: A retrospective analysis of 37 patients …

Malignancies of the large intestine assume a major importance because of their frequency in
the general population. The types of malignancies that may occur can be classified as …

Purpose: Patients with colorectal cancer have a high risk of developing metachronous
neoplasms. Identification of predictive factors associated with such conditions would allow …

Evaluating the risk of colorectal metachronous adenoma (MA), which is a precancerous
lesion, is necessary for metachronous colorectal cancer (CRC) precaution among CRC …