[HTML][HTML] Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants
Malaria—a parasite vector-borne disease—is a global health problem, and Plasmodium
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …
[HTML][HTML] The role of different components of the immune system against Plasmodium falciparum malaria: Possible contribution towards malaria vaccine development
WL Mandala, V Harawa, F Dzinjalamala… - Molecular and …, 2021 - Elsevier
Plasmodium falciparum malaria still remains a major global public health challenge with
over 220 million new cases and well over 400,000 deaths annually. Most of the deaths occur …
over 220 million new cases and well over 400,000 deaths annually. Most of the deaths occur …
[HTML][HTML] Seven-year efficacy of RTS, S/AS01 malaria vaccine among young African children
Background The candidate malaria vaccine RTS, S/AS01 is being evaluated in order to
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
[HTML][HTML] Hitting hotspots: spatial targeting of malaria for control and elimination
Hitting Hotspots: Spatial Targeting of Malaria for Control and Elimination | PLOS Medicine Skip
to main content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special …
to main content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special …
Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities
Tools to reliably measure Plasmodium falciparum (Pf) exposure in individuals and
communities are needed to guide and evaluate malaria control interventions. Serologic …
communities are needed to guide and evaluate malaria control interventions. Serologic …
Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and …
DI Stanisic, FJI Fowkes, M Koinari, S Javati… - Infection and …, 2015 - Am Soc Microbiol
Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after
repeated exposure. Knowledge of the acquisition and nature of protective immune …
repeated exposure. Knowledge of the acquisition and nature of protective immune …
Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria
DK Raj, A Das Mohapatra, A Jnawali, J Zuromski… - Nature, 2020 - nature.com
Malaria caused by Plasmodium falciparum remains the leading single-agent cause of
mortality in children, yet the promise of an effective vaccine has not been fulfilled. Here …
mortality in children, yet the promise of an effective vaccine has not been fulfilled. Here …
Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection
DK Raj, CP Nixon, CE Nixon, JD Dvorin, CG DiPetrillo… - Science, 2014 - science.org
Novel vaccines are urgently needed to reduce the burden of severe malaria. Using a
differential whole-proteome screening method, we identified Plasmodium falciparum …
differential whole-proteome screening method, we identified Plasmodium falciparum …
[HTML][HTML] Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection
L Foquet, CC Hermsen, GJ van Gemert… - The Journal of …, 2014 - Am Soc Clin Investig
Malaria, which is the result of Plasmodium falciparum infection, is a global health threat that
resulted in 655,000 deaths and 216 million clinical cases in 2010 alone. Recent phase 3 …
resulted in 655,000 deaths and 216 million clinical cases in 2010 alone. Recent phase 3 …
[HTML][HTML] Pareto rules for malaria super-spreaders and super-spreading
Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An
80-20 “Pareto” rule has been proposed to describe this heterogeneity whereby 80% of …
80-20 “Pareto” rule has been proposed to describe this heterogeneity whereby 80% of …