Live-cell microscopy is a powerful tool that can reveal cellular behavior as well as the
underlying molecular processes. A key advantage of microscopy is that by visualizing …

While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …

Nuclear transport is facilitated by the Nuclear Pore Complex (NPC) and is essential for life in
eukaryotes. The NPC is a long-lived and exceptionally large structure. We asked whether …

Variation in gene copy number can alter gene expression and influence downstream
phenotypes; thus copy-number variation provides a route for rapid evolution if the benefits …

Much of biochemical regulation ultimately controls growth rate, particularly in microbes.
Although time-lapse microscopy visualises cells, determining their growth rates is …

Although cells respond specifically to environments, how environmental identity is encoded
intracellularly is not understood. Here, we study this organization of information in budding …

Biological organisms experience constantly changing environments, from sudden changes
in physiology brought about by feeding, to the regular rising and setting of the Sun, to …

The transduction time between signal initiation and final response provides valuable
information on the underlying signaling pathway, including its speed and precision …

Exposure of cells to diverse types of stressful environments differentially regulates cell fate.
Although many types of stresses causing this differential regulation are known, it is unknown …

To remain competitive, cells exposed to stress of varying duration, rapidity of onset, and
intensity, have to balance their expenditure on growth and proliferation versus stress …