Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

FE Poynton, SA Bright, S Blasco, DC Williams… - Chemical Society …, 2017 - pubs.rsc.org
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment

R Thapa, H Ali, O Afzal, AA Bhat, WH Almalki… - Journal of Nanoparticle …, 2023 - Springer
Breast cancer is the most common cancer among women and is typically managed through
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …

Noble metals in medicine: Latest advances

S Medici, M Peana, VM Nurchi, JI Lachowicz… - Coordination Chemistry …, 2015 - Elsevier
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Gated materials for on-command release of guest molecules

E Aznar, M Oroval, L Pascual, JR Murguía… - Chemical …, 2016 - ACS Publications
Multidisciplinary research at the forefront of the field of hybrid materials has paved the way to
the development of endless examples of smart devices. One appealing concept in this fertile …

Why develop photoactivated chemotherapy?

S Bonnet - Dalton Transactions, 2018 - pubs.rsc.org
Photoactivated chemotherapy is an approach where a biologically active compound is
protected against interaction with the cell environment by a light-cleavable protecting group …

A drug‐self‐gated mesoporous antitumor nanoplatform based on pH‐sensitive dynamic covalent bond

X Zeng, G Liu, W Tao, Y Ma, X Zhang… - Advanced Functional …, 2017 - Wiley Online Library
To achieve on‐demand drug release, mesoporous silica nanocarriers as antitumor platforms
generally need to be gated with stimuli‐responsive capping agents. Herein, a “smart” …

In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug

X Wu, X Sun, Z Guo, J Tang, Y Shen… - Journal of the …, 2014 - ACS Publications
In vivo monitoring of the biodistribution and activation of prodrugs is urgently required. Near
infrared (NIR) fluorescence-active fluorophores with excellent photostability are preferable …

Recent advances in ruthenium (II) and iridium (III) complexes containing nanosystems for cancer treatment and bioimaging

J Shen, TW Rees, L Ji, H Chao - Coordination chemistry reviews, 2021 - Elsevier
Ruthenium (II) and iridium (III) coordination compounds display excellent structural,
photophysical, and biological properties which make them highly promising as anticancer …