[HTML][HTML] Functional lipids in autoimmune inflammatory diseases
Lipids are apolar small molecules known not only as components of cell membranes but
also, in recent literature, as modulators of different biological functions. Herein, we focused …
also, in recent literature, as modulators of different biological functions. Herein, we focused …
Potential Roles of CD34+ Fibrocytes Masquerading as Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy
TJ Smith - The Journal of Clinical Endocrinology & Metabolism, 2019 - academic.oup.com
Context Orbital tissues in thyroid-associated ophthalmopathy exhibit particular reactivity and
undergo characteristic remodeling. Mechanisms underlying these changes have remained …
undergo characteristic remodeling. Mechanisms underlying these changes have remained …
LncRNA LPAL2/miR-1287-5p/EGFR axis modulates TED-derived orbital fibroblast activation through cell adhesion factors
N Wang, S Hou, X Qi, M Deng, J Cao… - The Journal of …, 2021 - academic.oup.com
Context The activation of orbital fibroblasts, the prime targets in thyroid eye disease (TED), is
central to its underlying pathogenesis. Objective We aimed to investigate the mechanism of …
central to its underlying pathogenesis. Objective We aimed to investigate the mechanism of …
[HTML][HTML] CD40 enhances sphingolipids in orbital fibroblasts: Potential role of sphingosine-1-Phosphate in inflammatory T-cell migration in graves' orbitopathy
S Plöhn, B Edelmann, L Japtok, X He… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: Graves' orbitopathy (GO) is an autoimmune orbital disorder associated with
Graves' disease caused by thyrotropin receptor autoantibodies. Orbital fibroblasts (OFs) and …
Graves' disease caused by thyrotropin receptor autoantibodies. Orbital fibroblasts (OFs) and …
Promoter methylation and expression of intercellular adhesion molecule 1 gene in blood of autoimmune thyroiditis patients
SM Shalaby, AMH Mackawy, DM Atef, RM Atef… - Molecular biology …, 2019 - Springer
Growing data supported that epigenetic modifications, including altered DNA methylation
have a potential role in the pathogenesis of autoimmune thyroid diseases (AITD). In the …
have a potential role in the pathogenesis of autoimmune thyroid diseases (AITD). In the …
Fingolimod improves the outcome of experimental Graves' disease and associated orbitopathy by modulating the autoimmune response to the thyroid-stimulating …
S Plöhn, M Hose, A Schlüter, L Michel, S Diaz-Cano… - Thyroid, 2019 - liebertpub.com
Graves' disease (GD) and Graves' orbitopathy are associated with stimulating thyrotropin
receptor (TSHR) autoantibodies and autoreactive T cells. Recent in vitro studies suggested …
receptor (TSHR) autoantibodies and autoreactive T cells. Recent in vitro studies suggested …
[HTML][HTML] Sphingolipids in thyroid eye disease
A Gulbins, GE Görtz, E Gulbins… - Frontiers in Endocrinology, 2023 - frontiersin.org
Graves' disease (GD) is caused by an autoimmune formation of autoantibodies and
autoreactive T-cells against the thyroid stimulating hormone receptor (TSHR). The …
autoreactive T-cells against the thyroid stimulating hormone receptor (TSHR). The …
[HTML][HTML] Chemokine expression during Adipogenesis and inflammation in orbital fibroblasts from patients with Graves' Orbitopathy
CE Lee, SH Choi, JS Yoon - Korean journal of ophthalmology: KJO, 2020 - ncbi.nlm.nih.gov
Purpose Chemokines are involved in the pathogenesis of various autoimmune diseases,
including Graves' orbitopathy (GO), but comprehensive analyses of the dynamics of these …
including Graves' orbitopathy (GO), but comprehensive analyses of the dynamics of these …
[PDF][PDF] The crucial role of sphingosine-1-phosphate and the therapeutic potential of fingolimod for Graves disease and associated orbitopathy
S Plöhn - 2019 - duepublico2.uni-due.de
1.1 Zusammenfassung Morbus Basedow (Graves disease) ist eine autoimmune
Schilddrüsenerkrankung, die durch stimulierende Autoantikörper ausgelöst wird, die gegen …
Schilddrüsenerkrankung, die durch stimulierende Autoantikörper ausgelöst wird, die gegen …
[引用][C] CD40 Enhances Sphingolipids in Orbital Fibroblasts
S Plöhn, B Edelmann, L Japtok, X He, M Hose…