Composition, structure and function of the corneal stroma

EM Espana, DE Birk - Experimental eye research, 2020 - Elsevier
No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

The molecular basis of corneal transparency

JR Hassell, DE Birk - Experimental eye research, 2010 - Elsevier
The cornea consists primarily of three layers: an outer layer containing an epithelium, a
middle stromal layer consisting of a collagen-rich extracellular matrix (ECM) interspersed …

MINI REVIEW Keratan sulfate: structure, biosynthesis, and function

JL Funderburgh - Glycobiology, 2000 - academic.oup.com
The last 5 years have seen a marked increase in research on keratan sulfate (KS) and a
concomitant increase in our understanding of the range of molecules that carry this …

Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro

DM Snow, V Lemmon, DA Carrino, AI Caplan… - Experimental …, 1990 - Elsevier
In vivo studies of the roof plate of the spinal cord and midline optic tectum in rodent and the
developing subplate in the telencephalon of the chick showed that two glycosaminoglycans …

Regulation of corneal stroma extracellular matrix assembly

S Chen, MJ Mienaltowski, DE Birk - Experimental eye research, 2015 - Elsevier
The transparent cornea is the major refractive element of the eye. A finely controlled
assembly of the stromal extracellular matrix is critical to corneal function, as well as in …

[HTML][HTML] Collagens and proteoglycans of the corneal extracellular matrix

YM Michelacci - Brazilian Journal of Medical and Biological Research, 2003 - SciELO Brasil
The cornea is a curved and transparent structure that provides the initial focusing of a light
image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth …

Molecular and cellular characterization of the glial roof plate of the spinal cord and optic tectum: a possible role for a proteoglycan in the development of an axon …

DM Snow, DA Steindler, J Silver - Developmental biology, 1990 - Elsevier
Certain types of glial structures, located at strategic positions along axon pathways, may
provide the mechanical and/or chemical elements for the construction of barriers which can …

cDNA to chick lumican (corneal keratan sulfate proteoglycan) reveals homology to the small interstitial proteoglycan gene family and expression in muscle and …

TC Blochberger, JP Vergnes, J Hempel… - Journal of Biological …, 1992 - ASBMB
A 1.9-kb cDNA clone to chick lumican (keratan sulfate proteoglycan) was isolated by
screening an expressing vector library made from chick corneal RNA with antiserum to chick …

The engineering of organized human corneal tissue through the spatial guidance of corneal stromal stem cells

J Wu, Y Du, SC Watkins, JL Funderburgh, WR Wagner - Biomaterials, 2012 - Elsevier
Corneal stroma is an avascular connective tissue characterized by layers of highly
organized parallel collagen fibrils, mono-disperse in diameter with uniform local interfibrillar …

Proteoglycans in dentinogenesis

G Embery, R Hall, R Waddington… - Critical Reviews in …, 2001 - journals.sagepub.com
The predominant proteoglycans present in predentin and dentin are the chondroitin-
sulphate-rich decorin and biglycan and the keratan-sulphate-rich lumican and fibromodulin …