Attempts are being made to develop therapeutic proteins for cancer, hepatitis, and
autoimmune conditions, but their clinical applications are limited, except in the cases of …

Abstract α-Thalassaemia 1 genetic disorder occurs when there is a deletion of two linked α-
globin genes. The interaction between these abnormal genes leads to the most severe type …

Proteomics-based analysis is currently the most promising approach for identifying
biomarker proteins for use in drug development. However, many candidate biomarker …

We sought to demonstrate the ability of levels of Hb Bart's and ζ-globin chain quantified by
enzyme-linked immunosorbent assay (ELISA) in detecting α-thalassemia in β-thalassemia …

α thalassemia is probably the most common of all single-gene disorders throughout the
world. Most incidences of α thalassemia arise from the deletion of one (-α) or both (--) of the …

Although the most common types of oral disease are dental caries and periodontal disease,
oral cancer such as squamous cell carcinoma (SCC) is associated with an unfavorable …

The invention provides a device and method for the rapid identification of patients suspected
of having thalassemia. The invention provides a test strip for the aqueous detection of …

Using a mouse monoclonal antibody (mAb)(“2D4”) with high specific reactivity to Hb Bart's
and a rabbit polyclonal antibody (“RPB”) with high reactivity to Hb Bart's but low reactivity to …

Monoclonal antibodies against α-globin containing human Hbs, named AMS-Alpha1 and
AMS-Alpha 2, were produced by the hybridoma technique using spleen cells enriched by …