Carbapenem-resistant Enterobacteriaceae infections have spread globally, leaving
polymyxins, including colistin, as 'last-resort treatments'. Emerging colistin resistance raises …

A comprehensive review of drug penetration into pulmonary epithelial lining fluid (ELF) was
previously published in 2011. Since then, an extensive number of studies comparing plasma …

Abstract The Thailand Antimicrobial Resistance (AMR) Containment and Prevention
Program was founded to develop, co-ordinate and implement AMR Containment and …

Highlights•Frequent use of carbapenem increases selection of carbapenem resistant
Enterobacterales•To alleviate this, we reviewed alternative strategies against complicated …

The in vitro study of sitafloxacin against carbapenem-resistant (CR) Acinetobacter
baumannii demonstrated activity against most strains of CR A. baumannii, and the …

Background The overuse and misuse of carbapenems have contributed to the antibiotic
resistance crisis. The role of oral fluoroquinolones as a switch therapy for the treatment of …

To investigate antimicrobial susceptibility patterns of various bacterial pathogens isolated
from complicated urinary tract infection (UTI) cases, the Japanese Society of Chemotherapy …

Objective The emergence of resistance to colistin, the last resort for treating severe
infections caused by Pseudomonas aeruginosa, poses a significant threat to public health …

Background The conventional antibiotic regimen for community-acquired upper urinary tract
infections with moderate severity in Thailand is parenteral ceftriaxone (CTRX) for several …

Sitafloxacin is a 4th generation fluoroquinolone antibiotic with broad activity against a wide
range of Gram-negative and Gram-positive bacteria. It is approved in Japan and used to …