Detecting biothreat agents: From current diagnostics to developing sensor technologies

SA Walper, G Lasarte Aragonés, KE Sapsford… - ACS …, 2018 - ACS Publications
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Strategies for surface immobilization of whole bacteriophages: A review

L O'connell, PR Marcoux… - ACS Biomaterials Science …, 2021 - ACS Publications
Bacteriophage immobilization is a key unit operation in emerging biotechnologies, enabling
new possibilities for biodetection of pathogenic microbes at low concentration, production of …

Non-toxic immunosensor for highly efficient detection of tetrodotoxin by electrochemical and colorimetric dual-mode sensing platform

YR Li, XX Dong, WY Cai, YF Liang, XH Chen… - Sensors and Actuators B …, 2023 - Elsevier
Antibody-based immunoassay is an important tool for detecting tetrodotoxin (TTX), a strong
neurotoxic with high mortality rate. However, the traditional immunoassays always suffer …

The virulence index: a metric for quantitative analysis of phage virulence

ZJ Storms, MR Teel, K Mercurio, D Sauvageau - Phage, 2020 - liebertpub.com
Background: One of the main challenges in developing phage therapy and manufacturing
phage products is the reliable evaluation of their efficacy, performance, and quality. Since …

Direct detection of Salmonella typhimurium on fresh produce using phage-based magnetoelastic biosensors

S Li, Y Li, H Chen, S Horikawa, W Shen… - Biosensors and …, 2010 - Elsevier
Current bacterial detection methods require the collection of samples followed by
preparation and analysis in the laboratory, both time and labour consuming steps. More …

Microencapsulation of Clostridium difficile specific bacteriophages using microfluidic glass capillary devices for colon delivery using pH triggered release

GK Vinner, GT Vladisavljević, MRJ Clokie, DJ Malik - PLoS One, 2017 - journals.plos.org
The prevalence of pathogenic bacteria acquiring multidrug antibiotic resistance is a global
health threat to mankind. This has motivated a renewed interest in developing alternatives to …

[HTML][HTML] Modeling tailed bacteriophage adsorption: Insight into mechanisms

ZJ Storms, D Sauvageau - Virology, 2015 - Elsevier
The process of a bacteriophage attaching to its host cell is a combination of physical
diffusion, biochemical surface interactions, and reaction-induced conformational changes in …

Going viral: Designing bioactive surfaces with bacteriophage

Z Hosseinidoust, ALJ Olsson, N Tufenkji - Colloids and Surfaces B …, 2014 - Elsevier
Bacteriophage-functionalized bioactive surfaces are functional materials that can be used as
antimicrobial surfaces in medical applications (eg, indwelling medical devices or wound …

Phage-based electrochemical sensors: A review

J Xu, Y Chau, Y Lee - Micromachines, 2019 - mdpi.com
Phages based electrochemical sensors have received much attention due to their high
specificity, sensitivity and simplicity. Phages or bacteriophages provide natural affinity to …

Magnetostrictive resonators as sensors and actuators

K Zhang, L Zhang, L Fu, S Li, H Chen… - Sensors and Actuators A …, 2013 - Elsevier
Two types of magnetostrictive resonators–magnetostrictive microcantilever (MSMC) and
magnetostrictive particle (MSP)–have been introduced as sensor platforms. Their principles …