Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …

Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

It is well established that organs of future metastasis are not passive receivers of circulating
tumour cells, but are instead selectively and actively modified by the primary tumour before …

Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …

Most cancer-related deaths are a result of metastasis, and thus the importance of this
process as a target of therapy cannot be understated. By asking 'how can we effectively treat …

Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being
naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis …

Targeting exosome biogenesis and release may have potential clinical implications for
cancer therapy. Herein, we have optimized a quantitative high throughput screen (qHTS) …

During cancer progression, many tumours shed circulating tumour cells (CTCs) and other
biomarkers into the bloodstream. The analysis of CTCs offers the prospect of collecting a …

Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …