[HTML][HTML] Sesquiterpene nootkatone counteracted the melamine-induced neurotoxicity via repressing of oxidative stress, inflammatory, and apoptotic trajectories

OA Habotta, A Abdeen, AA El-Hanafy, N Yassin… - Biomedicine & …, 2023 - Elsevier
Melamine (ML), a chemical substance of high nitrogen content, is used as a food adulterant.
Former evidences implied that ML could induce a variety of toxic effects including …

Screening for polystyrene nanoparticle toxicity on kidneys of adult male albino rats using histopathological, biochemical, and molecular examination results

YH Ahmed, ME El-Naggar, MM Rashad… - Cell and tissue …, 2022 - Springer
Abstract Polystyrene Nanoparticles (PS-NPs) used for packaging foam, disposable cups,
and food containers. Therefore, this study aimed to evaluate PS-NPs toxic effects on kidney …

Nootkatone mitigated melamine-evoked hepatotoxicity by featuring oxidative stress and inflammation interconnected mechanisms: in vivo and in silico approaches

OA Habotta, A Abdeen, AB Roomi, AI Elgndy… - Toxics, 2023 - mdpi.com
Melamine (ML) is a common environmental contaminant, commonly used in food fraud,
representing a serious health hazard and jeopardizing human and animal health. Recently …

Nephroprotective effects of selenium nanoparticles against sodium arsenite-induced damages

S Li, X Dong, L Xu, Z Wu - International Journal of Nanomedicine, 2023 - Taylor & Francis
Introduction The potential effects of selenium nanoparticles (SeNPs) administration on
arsenic exposure-mediated nephrotoxicity by alleviating fibrosis, inflammation, oxidative …

Angelica sinensis polysaccharides modified selenium nanoparticles for effective prevention of acute liver injury

Y Xu, XC Wang, W Jiang, JN Hu - International Journal of Biological …, 2024 - Elsevier
As a global public health issue, the treatment of acute liver injury (ALI) is severely limited
due to the lack of specific drugs. In order to address the challenges, innovative strategies for …

Effect of Administration of Selenium Nanoparticles Synthesized Using Onion Extract on Biochemical and Inflammatory Parameters in Mice Fed with High-Fructose Diet: In Vivo …

F Martínez-Esquivias, A Perez-Larios… - … Trace Element Research, 2024 - Springer
Fructose consumption has increased globally and has been linked to obesity, insulin
resistance, and diabetes. Selenium nanoparticles (SeNPs) can regulate glucose and lipid …

The effect of Alnus incana (L.) Moench extracts in ameliorating iron overload-induced hepatotoxicity in male albino rats

F Abo-Elghiet, SA Mohamed, NAE Yasin, A Temraz… - Scientific Reports, 2023 - nature.com
Iron overload causes multiorgan dysfunction and serious damage. Alnus incana from the
family Betulaceae, widely distributed in North America, is used for treating diseases. In this …

Ameliorative effect of N‐acetylcysteine on the testicular tissue of adult male albino rats after glyphosate‐based herbicide exposure

AR Hashim, DW Bashir, NAE Yasin… - … of Biochemical and …, 2022 - Wiley Online Library
Glyphosate (GLP) is a broad‐spectrum herbicide that is frequently used in crop production,
but its residues remain in foodstuffs. This, in turn, has led to potential adverse effects on both …

Implication of nanoparticles to combat chronic liver and kidney diseases: progress and perspectives

M Hashim, H Mujahid, S Hassan, S Bukhari, I Anjum… - Biomolecules, 2022 - mdpi.com
Liver and kidney diseases are the most frequently encountered problems around the globe.
Damage to the liver and kidney may occur as a result of exposure to various drugs …

Nootkatone Counteracts Melamine-Mediated Nephrotoxicity via Modulation of Intermediate Filament Proteins, Oxidative, Inflammatory, and Apoptotic Events

D Abdelrahaman, OA Habotta, A Ateya… - Drug Design …, 2024 - Taylor & Francis
Background Nootkatone (NK), a bioactive sesquiterpene ketone, is a major ingredient in
grapefruit that has distinguished biological activities. Melamine (MM), a food adulterant, was …