Inhibitors of melanogenesis: an updated review

T Pillaiyar, V Namasivayam, M Manickam… - Journal of medicinal …, 2018 - ACS Publications
Melanins are pigment molecules that determine the skin, eye, and hair color of the human
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …

[HTML][HTML] Natural products in cosmetics

JK Liu - Natural products and bioprospecting, 2022 - Springer
The global cosmetics market reached US 500billionin2017andisexpectedtoexceedUS 800
billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as …

Recent development of signaling pathways inhibitors of melanogenesis

T Pillaiyar, M Manickam, SH Jung - Cellular signalling, 2017 - Elsevier
Human skin, eye and hair color rely on the production of melanin, depending on its quantity,
quality, and distribution, Melanin plays a monumental role in protecting the skin against the …

Targeting tyrosinase in hyperpigmentation: Current status, limitations and future promises

S Zolghadri, M Beygi, TF Mohammad… - Biochemical …, 2023 - Elsevier
Hyperpigmentation is a common and distressing dermatologic condition. Since tyrosinase
(TYR) plays an essential role in melanogenesis, its inhibition is considered a logical …

[HTML][HTML] Overview of skin whitening agents: Drugs and cosmetic products

C Couteau, L Coiffard - Cosmetics, 2016 - mdpi.com
Depigmentation and skin lightening products, which have been in use for ages in Asian
countries where skin whiteness is a major esthetic criterion, are now also highly valued by …

[HTML][HTML] Skin protective effect of epigallocatechin gallate

E Kim, K Hwang, J Lee, SY Han, EM Kim… - International journal of …, 2018 - mdpi.com
Epigallocatechin gallate (EGCG) is a catechin and an abundant polyphenol in green tea.
Although several papers have evaluated EGCG as a cosmetic constituent, the skin hydration …

Downregulation of melanogenesis: drug discovery and therapeutic options

T Pillaiyar, M Manickam, SH Jung - Drug Discovery Today, 2017 - Elsevier
Highlights•Different melanogenesis signaling pathways.•Human tyrosinase inhibitors have
been discussed.•Drug repositioning has been applied to find new agents.Melanin, primarily …

Potential application of natural bioactive compounds as skin‐whitening agents: A review

W Zhao, A Yang, J Wang, D Huang… - Journal of Cosmetic …, 2022 - Wiley Online Library
Background Melanin is a skin pigment that gives color to the skin, hair, and eyes. The
accumulation or over production of melanin can lead to aesthetic problems as well as …

Ganoderma lucidum polysaccharide inhibits UVB‐induced melanogenesis by antagonizing cAMP/PKA and ROS/MAPK signaling pathways

S Hu, J Huang, S Pei, Y Ouyang, Y Ding… - Journal of Cellular …, 2019 - Wiley Online Library
Ultraviolet (UV)‐induced pigmentation is very common in clinical practice, but the current
treatments are rarely effective, accompanied by some side effects. Ganoderma lucidum …

[HTML][HTML] The modulation of melanogenesis in B16 cells upon treatment with plant extracts and isolated plant compounds

A Merecz-Sadowska, P Sitarek, T Kowalczyk, K Zajdel… - Molecules, 2022 - mdpi.com
Plants are a rich source of secondary metabolites that exhibit numerous desired properties.
The compounds may influence the biology of melanocytes, pigment cells that produce …