Bio-inspired hemocompatible surface modifications for biomedical applications

M Douglass, M Garren, R Devine, A Mondal… - Progress in materials …, 2022 - Elsevier
When blood first encounters the artificial surface of a medical device, a complex series of
biochemical reactions is triggered, potentially resulting in clinical complications such as …

Nitric oxide release: Part I. Macromolecular scaffolds

DA Riccio, MH Schoenfisch - Chemical Society Reviews, 2012 - pubs.rsc.org
The roles of nitric oxide (NO) in physiology and pathophysiology merit the use of NO as a
therapeutic for certain biomedical applications. Unfortunately, limited NO payloads, too rapid …

Glucose‐responsive sequential generation of hydrogen peroxide and nitric oxide for synergistic cancer starving‐like/gas therapy

W Fan, N Lu, P Huang, Y Liu, Z Yang… - Angewandte Chemie …, 2017 - Wiley Online Library
Glucose is a key energy supplier and nutrient for tumor growth. Herein, inspired by the
glucose oxidase (GOx)‐assisted conversion of glucose into gluconic acid and toxic H2O2, a …

Nanoscale coordination polymers for synergistic NO and chemodynamic therapy of liver cancer

Y Hu, T Lv, Y Ma, J Xu, Y Zhang, Y Hou, Z Huang… - Nano Letters, 2019 - ACS Publications
Nitric oxide (NO) induces a multitude of antitumor activities, encompassing the induction of
apoptosis, sensitization to chemo-, radio-, or immune-therapy, and inhibition of metastasis …

Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO)

Y Wo, EJ Brisbois, RH Bartlett, ME Meyerhoff - Biomaterials science, 2016 - pubs.rsc.org
Biomedical devices are essential for patient diagnosis and treatment; however, when blood
comes in contact with foreign surfaces or homeostasis is disrupted, complications including …

Semiconducting polymer nanotheranostics for NIR-II/Photoacoustic imaging-guided photothermal initiated nitric oxide/photothermal therapy

J Li, R Jiang, Q Wang, X Li, X Hu, Y Yuan, X Lu… - Biomaterials, 2019 - Elsevier
Gasotransmitters with their cytotoxicity in high concentration have become the focus of
attention. For such concentration depended therapy, how to effectively deliver gases and …

Biofunctionalization of biomaterials for accelerated in situ endothelialization: a review

A de Mel, G Jell, MM Stevens, AM Seifalian - Biomacromolecules, 2008 - ACS Publications
The higher patency rates of cardiovascular implants, including vascular bypass grafts,
stents, and heart valves are related to their ability to inhibit thrombosis, intimal hyperplasia …

Polymers incorporating nitric oxide releasing/generating substances for improved biocompatibility of blood-contacting medical devices

MC Frost, MM Reynolds, ME Meyerhoff - Biomaterials, 2005 - Elsevier
The current state-of-the-art with respect to the preparation, characterization and biomedical
applications of novel nitric oxide (NO) releasing or generating polymeric materials is …

Light-controlled nitric oxide delivering molecular assemblies

S Sortino - Chemical Society Reviews, 2010 - pubs.rsc.org
The multiple roles nitric oxide (NO) plays as a bioregulatory, anticancer, antimicrobial and
antioxidant agent has triggered an explosive interest in recent years in compounds able to …

Tunable Nitric Oxide Release from S-Nitroso-N-acetylpenicillamine via Catalytic Copper Nanoparticles for Biomedical Applications

J Pant, MJ Goudie, SP Hopkins… - … applied materials & …, 2017 - ACS Publications
The quest for novel therapies to prevent bacterial infections and blood clots (thrombosis) is
of utmost importance in biomedical research due to the exponential growth in the cases of …