[HTML][HTML] Delivering safer immunotherapies for cancer

L Milling, Y Zhang, DJ Irvine - Advanced drug delivery reviews, 2017 - Elsevier
Cancer immunotherapy is now a powerful clinical reality, with a steady progression of new
drug approvals and a massive pipeline of additional treatments in clinical and preclinical …

Role of nitric oxide in IL-2 therapy-induced capillary leak syndrome

A Orucevic, PK Lala - Cancer and Metastasis Reviews, 1998 - Springer
Nitric oxide (NO) is a potent short-lived and short range bioactive molecule, which plays a
key role in physiological and pathological processes including inflammation and cancer …

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site

C Jackaman, AM Lew, Y Zhan, JE Allan… - International …, 2008 - academic.oup.com
Anti-cancer immunotherapies aim to generate resolution of all existing tumors, including
inaccessible ones, and provide long-term protection against recurrence. This is rarely …

Цитокины и система гемостаза I. Цитокины и сосудисто-тромбоцитарный гемостаз

Б Кузник - Тромбоз, гемостаз и реология, 2012 - elibrary.ru
В обзоре представлены сведения об основных функциях цитокинов и их влиянии на
сосудисто-тромбоцитарный гемостаз в эксперименте и клинике. На основании …

NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthesis, ameliorates interleukin 2-induced capillary leakage and reduces tumour growth in …

A Orucevic, PK Lala - British journal of cancer, 1996 - nature.com
We tested whether NG-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide
(NO) synthesis, can prevent interleukin 2 (IL-2)-induced capillary leakage in tumour-bearing …

Dysregulation of growth and development in HIV-infected children

S Hirschfeld - The Journal of nutrition, 1996 - Elsevier
Growth dysregulation is quite common in HIV-infected children and growth failure is one of
the most sensitive indicators of disease progression. Beginning at birth, HIV-infected infants …

Interleukin-7 induces differential lymphokine-activated killer cell activity against human melanoma cells, keratinocytes, and endothelial cells

D Schadendorf, M Böhm, P Möller, T Grünewald… - Journal of investigative …, 1994 - Elsevier
To assess the potential role of interleukin (IL)-7 in immunotherapy of human malignant
melanoma, we have examined the lymphokine-activated killer (LAK) cell sensitivity of four …

Effects of interleukin‐2 administration on platelet function in cancer patients

L Oleksowicz, D Zuckerman, Z Mrowiec… - American journal of …, 1994 - Wiley Online Library
Platelet function in 16 patients with metastatlc renal cell carcinoma and melanoma was
studied sequentially over the first 96 hr of treatment with moderate and highdose inter‐leukin …

Bovine microvascular endothelial cells of separate morphology differ in growth and response to the action of interferon-γ

AM Fenyves, M Saxer, K Spanel-Borowski - Experientia, 1994 - Springer
Five cell types recently isolated from the bovine corpus luteum differed in their epithelioid
morphology and their cytoskeleton, but shared common criteria of microvascular endothelial …

Interference with c-myc expression and RB phosphorylation during TNF-mediated growth arrest in human endothelial cells

R López-Marure, AE Bernal, A Zentella - Biochemical and biophysical …, 1997 - Elsevier
Incorporation of [3H]-thymidine into DNA in non-synchronized cultures of human endothelial
cells was blocked by a 24 h exposure to TNF in a dose dependent manner that resulted in …