CD4+T Cells: Differentiation and Functions
RV Luckheeram, R Zhou, AD Verma… - Journal of Immunology …, 2012 - Wiley Online Library
CD4+ T cells are crucial in achieving a regulated effective immune response to pathogens.
Naive CD4+ T cells are activated after interaction with antigen‐MHC complex and …
Naive CD4+ T cells are activated after interaction with antigen‐MHC complex and …
Memory CD4+ T Cells in Immunity and Autoimmune Diseases
I Raphael, RR Joern, TG Forsthuber - Cells, 2020 - mdpi.com
CD4+ T helper (Th) cells play central roles in immunity in health and disease. While much is
known about the effector function of Th cells in combating pathogens and promoting …
known about the effector function of Th cells in combating pathogens and promoting …
Immunogenic and reactogenic efficacy of Covaxin and Covishield: a comparative review
S Das, SS Kar, S Samanta, J Banerjee, B Giri… - Immunologic …, 2022 - Springer
SARS-CoV-2 is an RNA virus that was identified for the first time in December 2019 in
Wuhan, China. The World Health Organization (WHO) labeled the novel coronavirus …
Wuhan, China. The World Health Organization (WHO) labeled the novel coronavirus …
Bystander CD4+ T cells: crossroads between innate and adaptive immunity
T cells are the central mediators of both humoral and cellular adaptive immune responses.
Highly specific receptor-mediated clonal selection and expansion of T cells assure antigen …
Highly specific receptor-mediated clonal selection and expansion of T cells assure antigen …
The immunogenicity of humanized and fully human antibodies: residual immunogenicity resides in the CDR regions
FA Harding, MM Stickler, J Razo, R DuBridge - MAbs, 2010 - Taylor & Francis
Monoclonal antibodies represent an attractive therapeutic tool as they are highly specific for
their targets, convey effector functions and enjoy robust manufacturing procedures …
their targets, convey effector functions and enjoy robust manufacturing procedures …
Nanoparticles target distinct dendritic cell populations according to their size
V Manolova, A Flace, M Bauer… - European journal of …, 2008 - Wiley Online Library
The efficiency of a vaccine largely depends on the appropriate targeting of the innate
immune system, mainly through prolonged delivery of antigens and immunomodulatory …
immune system, mainly through prolonged delivery of antigens and immunomodulatory …
Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin
S Colombetti, V Basso, DL Mueller… - The Journal of …, 2006 - journals.aai.org
Proliferation of Ag-specific T cells is central to the development of protective immunity. The
concomitant stimulation of the TCR and CD28 programs resting T cells to IL-2-driven clonal …
concomitant stimulation of the TCR and CD28 programs resting T cells to IL-2-driven clonal …
Immune response and immunopathology during toxoplasmosis
Toxoplasma gondii is a protozoan parasite of medical and veterinary significance that is
able to infect any warm-blooded vertebrate host. In addition to its importance to public …
able to infect any warm-blooded vertebrate host. In addition to its importance to public …
The NOD mouse: a model of immune dysregulation
MS Anderson, JA Bluestone - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Autoimmunity is a complex process that likely results from the summation of
multiple defective tolerance mechanisms. The NOD mouse strain is an excellent model of …
multiple defective tolerance mechanisms. The NOD mouse strain is an excellent model of …
[HTML][HTML] Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells
Listeria monocytogenes infection generates T helper 1 (Th1) effector memory cells and CC
chemokine receptor 7 (CCR7)+ cells resembling central memory cells. We tracked …
chemokine receptor 7 (CCR7)+ cells resembling central memory cells. We tracked …