The properties of pyrimidine and pyrazine derivatives responsible for the existence of
antituberculosis activity are considered. Examples of synthesis and biological activity of the …

The unusual structure and chemical composition of the mycobacterial cell wall, the tedious
duration of therapy, and resistance developed by the microorganism have made the …

Pyrazinamide analogs 5a–h have been successfully synthesized by the Yamaguchi
esterification method with yields ranging from 6% to 86%. Among pyrazinamides 5a–h …

Infectious diseases, such as tuberculosis and invasive mycoses, represent serious health
problems. As a part of our long-term efforts to find new agents for the treatment of these …

A series of sixteen pyrazinamide analogues with the-CONH-linker connecting the pyrazine
and benzene rings was synthesized by the condensation of chlorides of substituted …

The Fourier transform infrared spectra of the compounds 2-(5-phenyl-1, 3, 4-oxadiazol-2-yl)
pyrazine (PHOXPY), 2-(5-styryl-1, 3, 4-oxadiazol-2-yl) pyrazine (STOXPY) and 2-(5-(furan-2 …

Substituted pyrazinecarboxamides markedly influenced production of flavonolignans in
Silybum marianum callus and suspension cultures. In this study the effect of two compounds …

The FT-IR spectral analysis and theoretical calculations of the wavenumbers of three
oxadiazole derivatives, 2-(5-(2-chlorophenyl)-1, 3, 4-oxadiazol-2-yl) pyrazine …

Abstract The FT-IR and FT-Raman spectra of N-(3-iodo-4-methylphenyl) pyrazine-2-
carboxamide were recorded and the experimentally observed wavenumbers are compared …

The optimized molecular structure, vibrational frequencies, corresponding vibrational
assignments of N-[(4-(trifluoromethyl) phenyl] pyrazine-2-carboxamide have been …