Intrinsically photosensitive retinal ganglion cells of the human retina

LS Mure - Frontiers in neurology, 2021 - frontiersin.org
Light profoundly affects our mental and physical health. In particular, light, when not
delivered at the appropriate time, may have detrimental effects. In mammals, light is …

Standards in pupillography

C Kelbsch, T Strasser, Y Chen, B Feigl… - Frontiers in …, 2019 - frontiersin.org
The number of research groups studying the pupil is increasing, as is the number of
publications. Consequently, new standards in pupillography are needed to formalize the …

Light-induced pupillary responses in Alzheimer's disease

PS Chougule, RP Najjar, MT Finkelstein… - Frontiers in …, 2019 - frontiersin.org
The impact of Alzheimer's disease (AD) on the pupillary light response (PLR) is
controversial, being dependent on the stage of the disease and on the experimental …

Chromatic pupillometry methods for assessing photoreceptor health in retinal and optic nerve diseases

AV Rukmini, D Milea, JJ Gooley - Frontiers in neurology, 2019 - frontiersin.org
The pupillary light reflex is mediated by melanopsin-containing intrinsically-photosensitive
retinal ganglion cells (ipRGCs), which also receive input from rods and cones. Melanopsin …

[HTML][HTML] Pupillary light reflex as a diagnostic aid from computational viewpoint: A systematic literature review

HM Pinheiro, RM da Costa - Journal of Biomedical Informatics, 2021 - Elsevier
This work presents a detailed and complete review of publications on pupillary light reflex
(PLR) used to aid diagnoses. These are computational techniques used in the evaluation of …

Melanopsin retinal ganglion cells and pupil: clinical implications for neuro-ophthalmology

C La Morgia, V Carelli, M Carbonelli - Frontiers in neurology, 2018 - frontiersin.org
Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs that
mediate many relevant non-image forming functions of the eye, including the pupillary light …

[HTML][HTML] Photoreceptor contributions to the human pupil light reflex

PA Barrionuevo, LA Issolio, C Tripolone - Journal of Photochemistry and …, 2023 - Elsevier
The pupil reacts to the amount of light reaching the eye. It reduces its size when the light is
high and dilates at low light levels to allow the entrance of more photons. This behavior is …

Melanopsin photoreception differentially modulates rod-mediated and cone-mediated human temporal vision

S Uprety, P Adhikari, B Feigl, AJ Zele - Iscience, 2022 - cell.com
To evaluate the nature of interactions between visual pathways transmitting the slower
melanopsin and faster rod and cone signals, we implement a temporal phase summation …

Artificial intelligence and deep learning in glaucoma: current state and future prospects

MJA Girard, L Schmetterer - Progress in Brain Research, 2020 - Elsevier
Over the past few years, there has been an unprecedented and tremendous excitement for
artificial intelligence (AI) research in the field of Ophthalmology; this has naturally been …

Handheld chromatic pupillometry can accurately and rapidly reveal functional loss in glaucoma

RP Najjar, AV Rukmini, MT Finkelstein… - British Journal of …, 2023 - bjo.bmj.com
Background/aims Early detection and treatment of glaucoma can delay vision loss. In this
study, we evaluate the performance of handheld chromatic pupillometry (HCP) for the …