Nitrite reduction and cardiovascular protection
Inorganic nitrite, a metabolite of endogenously produced nitric oxide (NO) from NO
synthases (NOS), provides the largest endocrine source of directly bioavailable NO. The …
synthases (NOS), provides the largest endocrine source of directly bioavailable NO. The …
Splanchnic vein thrombosis associated with myeloproliferative neoplasms
D Tremblay, A Winters, JD Beckman, L Naymagon… - Thrombosis …, 2022 - Elsevier
Splanchnic vein thrombosis (SVT) in the setting of myeloproliferative neoplasm (MPN) is a
unique clinical entity that requires close interdisciplinary coordination for proper diagnosis …
unique clinical entity that requires close interdisciplinary coordination for proper diagnosis …
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data
A Jordan, D Chen, QL Yi, T Kanias, MT Gladwin… - Vox …, 2016 - Wiley Online Library
Background and Objectives Quality control (QC) data collected by blood services are used
to monitor production and to ensure compliance with regulatory standards. We demonstrate …
to monitor production and to ensure compliance with regulatory standards. We demonstrate …
Global REACH 2018: high blood viscosity and hemoglobin concentration contribute to reduced flow-mediated dilation in high-altitude excessive erythrocytosis
JC Tremblay, RL Hoiland, CA Howe, GB Coombs… - …, 2019 - Am Heart Assoc
Excessive erythrocytosis (EE; hemoglobin concentration [Hb]≥ 21 g/dL in adult males) is
associated with increased cardiovascular risk in highlander Andeans. We sought to quantify …
associated with increased cardiovascular risk in highlander Andeans. We sought to quantify …
Optimization of cardiovascular risk factor management in patients with BCR:: ABL1 negative chronic myeloproliferative neoplasms, current knowledge, and …
I Krecak, S Verstovsek, M Lucijanic - Annals of hematology, 2024 - Springer
The exact prognostic role of cardiovascular (CV) risk factors in patients with BCR:: ABL1
negative chronic myeloproliferative neoplasms (MPNs) remains unknown as it is often …
negative chronic myeloproliferative neoplasms (MPNs) remains unknown as it is often …
Micro-and macrovascular function in the highest city in the world: a cross sectional study
Y Savina, AP Pichon, L Lemaire, CA Howe… - The Lancet Regional …, 2024 - thelancet.com
Background Since vascular responses to hypoxia in both healthy high-altitude natives and
chronic mountain sickness (a maladaptive high-altitude pathology characterised by …
chronic mountain sickness (a maladaptive high-altitude pathology characterised by …
Primary arterial hypertension and drug-induced hypertension in Philadelphia-negative classical myeloproliferative neoplasms: a systematic review
The impact of primary arterial hypertension (HTN) in myeloproliferative neoplasms (MPNs)
remains unclear, with scant literature available, mostly focusing on cardiovascular risk …
remains unclear, with scant literature available, mostly focusing on cardiovascular risk …
Emerging biomarkers of oxidative stress in acute and stable coronary artery disease: levels and determinants
V Lubrano, A Pingitore, I Traghella, S Storti, S Parri… - Antioxidants, 2019 - mdpi.com
Background: Oxidative stress is crucial in the pathogenesis of atherosclerosis and acute
myocardial infarction (AMI). Under the generic terms “oxidative stress”(OS), many …
myocardial infarction (AMI). Under the generic terms “oxidative stress”(OS), many …
[HTML][HTML] Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury
CM Shaver, N Wickersham, JB McNeil, H Nagata… - JCI insight, 2018 - ncbi.nlm.nih.gov
Primary graft dysfunction (PGD) is acute lung injury within 72 hours of lung transplantation.
We hypothesized that cell-free hemoglobin (CFH) contributes to PGD by increasing lung …
We hypothesized that cell-free hemoglobin (CFH) contributes to PGD by increasing lung …
Splanchnic Vein Thrombosis in Myeloproliferative Neoplasms: Treatment Considerations and Unmet Needs
A Liu, L Naymagon, D Tremblay - Cancers, 2022 - mdpi.com
Simple Summary Splanchnic vein thromboses (SVTs) are atypical clots associated with
myeloproliferative neoplasms (MPNs). However, there are no well-established guidelines on …
myeloproliferative neoplasms (MPNs). However, there are no well-established guidelines on …