Alternative methods of vaccine delivery: an overview of edible and intradermal vaccines

E Criscuolo, V Caputo, RA Diotti… - Journal of …, 2019 - Wiley Online Library
Vaccines are recognized worldwide as one of the most important tools for combating
infectious diseases. Despite the tremendous value conferred by currently available vaccines …

Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D

MD Slein, IM Backes, CR Garland, NS Kelkar… - Cell Reports …, 2024 - cell.com
Multiple failed herpes simplex virus (HSV) vaccine candidates induce robust neutralizing
antibody (Ab) responses in clinical trials, raising the hypothesis that Fc-domain-dependent …

Small molecule RAF265 as an antiviral therapy acts against HSV‐1 by regulating cytoskeleton rearrangement and cellular translation machinery

CC Li, XJ Chi, J Wang, AL Potter… - Journal of Medical …, 2023 - Wiley Online Library
Host‐targeting antivirals (HTAs) have received increasing attention for their potential as
broad‐spectrum antivirals that pose relatively low risk of developing drug resistance. The …

The molecular tweezer CLR01 inhibits antibody-resistant cell-to-cell spread of human cytomegalovirus

S Brenner, B Braun, C Read, T Weil, P Walther… - Viruses, 2021 - mdpi.com
Human cytomegalovirus (HCMV) uses two major ways for virus dissemination: infection by
cell-free virus and direct cell-to-cell spread. Neutralizing antibodies can efficiently inhibit …

Cell-to-cell spread blocking activity is extremely limited in the sera of herpes simplex virus 1 (HSV-1)-and HSV-2-infected subjects

E Criscuolo, M Castelli, RA Diotti, V Amato… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT Herpes simplex virus 1 (HSV-1) and HSV-2 can evade serum antibody-
mediated neutralization through cell-to-cell transmission mechanisms, which represent one …

A potent neutralizing and protective antibody against a conserved continuous epitope on HSV glycoprotein D

R Tian, F Ju, M Yu, Z Liang, Z Xu, M Zhao, Y Qin, Y Lin… - Antiviral Research, 2022 - Elsevier
Infections caused by herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) remain a
serious global health issue, and the medical countermeasures available thus far are limited …

Proper selection of in vitro cell model affects the characterization of the neutralizing antibody response against SARS-CoV-2

E Criscuolo, B Giuliani, D Ferrari, R Ferrarese… - Viruses, 2022 - mdpi.com
(1) Background: Our aim is the evaluation of the neutralizing activity of BNT162b2 mRNA
vaccine-induced antibodies in different in vitro cellular models, as this still represents one of …

Synergy evaluation of anti-Herpes Simplex Virus type 1 and 2 compounds acting on different steps of virus life cycle

E Criscuolo, N Clementi, N Mancini, R Burioni… - Antiviral research, 2018 - Elsevier
Despite the clinical need of novel and safe anti-herpetic compounds effective for treating
both primary infections and reactivations of Herpes Simplex Virus type 1 (HSV-1) and type 2 …

A human stem cell-derived neurosensory–epithelial circuitry on a chip to model herpes simplex virus reactivation

PG Mazzara, E Criscuolo, M Rasponi, L Massimino… - Biomedicines, 2022 - mdpi.com
Both emerging viruses and well-known viral pathogens endowed with neurotropism can
either directly impair neuronal functions or induce physio-pathological changes by diffusing …

[PDF][PDF] Proper Selection of In Vitro Cell Model Affects the Characterization of the Neutralizing Antibody Response against SARS-CoV-2. Viruses. 2022; 14 (6)

E Criscuolo, B Giuliani, D Ferrari, R Ferrarese… - 2022 - academia.edu
(1) Background: Our aim is the evaluation of the neutralizing activity of BNT162b2 mRNA
vaccine-induced antibodies in different in vitro cellular models, as this still represents one of …