Paranodal axoglial junctions, an essential component in axonal homeostasis
T Ishibashi, H Baba - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
In vertebrates, a high density of voltage-gated Na+ channel at nodes of Ranvier and of
voltage-gated K+ channel at juxtaparanodes is necessary for rapid propagation of action …
voltage-gated K+ channel at juxtaparanodes is necessary for rapid propagation of action …
Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability
Most mammalian neurons have a narrow axon, which constrains the passage of large
cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal …
cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal …
Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function
Axonal plasticity allows neurons to control their output, which critically determines the flow of
information in the brain. Axon diameter can be regulated by activity, yet how morphological …
information in the brain. Axon diameter can be regulated by activity, yet how morphological …
Understanding the pathogenic mechanisms and therapeutic effects in neurocysticercosis
G Castillo, L Fustamante… - Brain …, 2024 - Wiley Online Library
Despite being a leading cause of acquired seizures in endemic regions, the pathological
mechanisms of neurocysticercosis are still poorly understood. This study aims to investigate …
mechanisms of neurocysticercosis are still poorly understood. This study aims to investigate …
Preparation recombination human‐like collagen/fibroin scaffold and promoting the cell compatibility with osteoblasts
K Hu, M Hu, YH Xiao, Y Cui, J Yan… - … Research Part A, 2021 - Wiley Online Library
On this basis, a novel recombinant human‐like collagen (RHLC)/silk fibroin scaffold material
with high porosity and controllable aperture was prepared. The compatibility of osteoblasts …
with high porosity and controllable aperture was prepared. The compatibility of osteoblasts …
TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model
M Ye, Y Hu, B Zhao, Q Mou, Y Ni, J Luo… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: Glaucoma is the leading cause of irreversible blindness worldwide and is
characterized by progressive retinal ganglion cell (RGC) death and optic nerve …
characterized by progressive retinal ganglion cell (RGC) death and optic nerve …
Reaction time impairments in decision-making networks as a diagnostic marker for traumatic brain injuries and neurological diseases
The presence of diffuse Focal Axonal Swellings (FAS) is a hallmark cellular feature in many
neurological diseases and traumatic brain injury. Among other things, the FAS have a …
neurological diseases and traumatic brain injury. Among other things, the FAS have a …
Axons-on-a-chip for mimicking non-disruptive diffuse axonal injury underlying traumatic brain injury
Diffuse axonal injury (DAI) is the most severe pathological feature of traumatic brain injury
(TBI). However, how primary axonal injury is induced by transient mechanical impacts …
(TBI). However, how primary axonal injury is induced by transient mechanical impacts …
Functionality and Robustness of Injured Connectomic Dynamics in C. elegans: Linking Behavioral Deficits to Neural Circuit Damage
Using a model for the dynamics of the full somatic nervous system of the nematode C.
elegans, we address how biological network architectures and their functionality are …
elegans, we address how biological network architectures and their functionality are …
Modeling cognitive deficits following neurodegenerative diseases and traumatic brain injuries with deep convolutional neural networks
The accurate diagnosis and assessment of neurodegenerative disease and traumatic brain
injuries (TBI) remain open challenges. Both cause cognitive and functional deficits due to …
injuries (TBI) remain open challenges. Both cause cognitive and functional deficits due to …