Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

Purpose: Artificial intelligence (AI) has accelerated novel discoveries across multiple
disciplines including medicine. Clinical medicine suffers from a lack of AI-based …

High-grade gliomas are aggressive cancers that often become rapidly fatal. Immunotherapy
using CD8+ cytotoxic T lymphocytes (CTLs), engineered to express both herpes simplex …

Cancer progression is caused by genetic changes and associated with various alterations in
cell properties, which also affect a tumor's mechanical state. While an increased stiffness …

Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …

Background Gliomas are the most common type of malignant brain and other CNS tumors,
accounting for 80.8% of malignant primary brain and CNS tumors. They cause significant …

Abstract Purpose of Review: Brain tumors consist of a collection of neoplasms arising from
within the brain or from systemic tumors that have metastasized to the brain. This article …

Simple Summary The translocator protein (TSPO) has been under extensive investigation as
a specific marker in positron emission tomography (PET) to visualize brain lesions following …

Glioma accounts for the majority of human brain tumors. With prevailing treatment regimens,
the patients have poor survival rates. In spite of current development in mainstream glioma …

Chemotherapy and radiation remain as mainstays in the treatment of a variety of cancers
globally, yet some therapies exhibit limited specificity and result in harsh side effects in …