[HTML][HTML] Automating the design-build-test-learn cycle towards next-generation bacterial cell factories

N Gurdo, DC Volke, D McCloskey, PI Nikel - New Biotechnology, 2023 - Elsevier
Automation is playing an increasingly significant role in synthetic biology. Groundbreaking
technologies, developed over the past 20 years, have enormously accelerated the …

A selective review of multi-level omics data integration using variable selection

C Wu, F Zhou, J Ren, X Li, Y Jiang, S Ma - High-throughput, 2019 - mdpi.com
High-throughput technologies have been used to generate a large amount of omics data. In
the past, single-level analysis has been extensively conducted where the omics …

[HTML][HTML] Proteogenomic characterization of human early-onset gastric cancer

DG Mun, J Bhin, S Kim, H Kim, JH Jung, Y Jung… - Cancer cell, 2019 - cell.com
We report proteogenomic analysis of diffuse gastric cancers (GCs) in young populations.
Phosphoproteome data elucidated signaling pathways associated with somatic mutations …

A fully Bayesian latent variable model for integrative clustering analysis of multi-type omics data

Q Mo, R Shen, C Guo, M Vannucci, KS Chan… - …, 2018 - academic.oup.com
Identification of clinically relevant tumor subtypes and omics signatures is an important task
in cancer translational research for precision medicine. Large-scale genomic profiling …

A novel approach for data integration and disease subtyping

T Nguyen, R Tagett, D Diaz, S Draghici - Genome research, 2017 - genome.cshlp.org
Advances in high-throughput technologies allow for measurements of many types of omics
data, yet the meaningful integration of several different data types remains a significant …

Integrative subtype discovery in glioblastoma using iCluster

R Shen, Q Mo, N Schultz, VE Seshan, AB Olshen… - PloS one, 2012 - journals.plos.org
Large-scale cancer genome projects, such as the Cancer Genome Atlas (TCGA) project, are
comprehensive molecular characterization efforts to accelerate our understanding of cancer …

Deep-learning approach to identifying cancer subtypes using high-dimensional genomic data

R Chen, L Yang, S Goodison, Y Sun - Bioinformatics, 2020 - academic.oup.com
Motivation Cancer subtype classification has the potential to significantly improve disease
prognosis and develop individualized patient management. Existing methods are limited by …

Evaluation of integrative clustering methods for the analysis of multi-omics data

C Chauvel, A Novoloaca, P Veyre… - Briefings in …, 2020 - academic.oup.com
Recent advances in sequencing, mass spectrometry and cytometry technologies have
enabled researchers to collect large-scale omics data from the same set of biological …

Multi-omics clustering for cancer subtyping based on latent subspace learning

X Ye, Y Shang, T Shi, W Zhang, T Sakurai - Computers in Biology and …, 2023 - Elsevier
The increased availability of high-throughput technologies has enabled biomedical
researchers to learn about disease etiology across multiple omics layers, which shows …

Review of statistical learning methods in integrated omics studies (an integrated information science)

ISL Zeng, T Lumley - Bioinformatics and biology insights, 2018 - journals.sagepub.com
Integrated omics is becoming a new channel for investigating the complex molecular system
in modern biological science and sets a foundation for systematic learning for precision …