A review on the phytochemistry, pharmacology, and pharmacokinetics of amentoflavone, a naturally-occurring biflavonoid

S Yu, H Yan, L Zhang, M Shan, P Chen, A Ding, SFY Li - Molecules, 2017 - mdpi.com
Amentoflavone (C30H18O10) is a well-known biflavonoid occurring in many natural plants.
This polyphenolic compound has been discovered to have some important bioactivities …

Valorisation of softwood bark through extraction of utilizable chemicals. A review

M Jablonsky, J Nosalova, A Sladkova, A Haz… - Biotechnology …, 2017 - Elsevier
Softwood bark is an important source for producing chemicals and materials as well as
bioenergy. Extraction is regarded as a key technology for obtaining chemicals in general …

Anti-Biofilm and Antibacterial Activities of Cycas media R. Br Secondary Metabolites: In Silico, In Vitro, and In Vivo Approaches

NGM Attallah, OM Al-Fakhrany, E Elekhnawy… - Antibiotics, 2022 - mdpi.com
Enterococcus species possess many virulence factors that have an essential role in
exacerbating the infections caused by them. The current study aimed to evaluate the effect of …

Biological Evaluation, DFT Calculations and Molecular Docking Studies on the Antidepressant and Cytotoxicity Activities of Cycas pectinata Buch.-Ham. Compounds

J Rahman, AM Tareq, MM Hossain, SA Sakib… - Pharmaceuticals, 2020 - mdpi.com
Cycas pectinata Buch.-Ham. is commonly used in folk medicine against various disorders.
The present study investigated the antidepressant and cytotoxicity activity of methanol …

Antidiarrheal and antibacterial activities of Monterey cypress phytochemicals: in vivo and in vitro approach

EI Elmongy, WA Negm, E Elekhnawy, TA El-Masry… - Molecules, 2022 - mdpi.com
Monterey cypress (Cupressus macrocarpa) is a decorative plant; however, it possesses
various pharmacological activities. Therefore, we explored the phytochemical profile of C …

Sotetsuflavone suppresses invasion and metastasis in non-small-cell lung cancer A549 cells by reversing EMT via the TNF-α/NF-κB and PI3K/AKT signaling pathway

S Wang, Y Yan, Z Cheng, Y Hu, T Liu - Cell death discovery, 2018 - nature.com
Epithelial-mesenchymal transition (EMT) is associated with tumor invasion and metastasis,
and offers insight into novel strategies for cancer treatment. Sotetsuflavone was isolated …

Investigation of the Antibacterial Activity and Efflux Pump Inhibitory Effect of Cycas thouarsii R.Br. Extract against Klebsiella pneumoniae Clinical Isolates

WA Negm, M El-Aasr, AA Kamer, E Elekhnawy - Pharmaceuticals, 2021 - mdpi.com
The vast spread of multidrug-resistant bacteria has encouraged researchers to explore new
antimicrobial compounds. This study aimed to investigate the phytochemistry and …

[HTML][HTML] Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like …

S Anzilotti, V Valente, P Brancaccio, C Franco… - Biomedicine & …, 2023 - Elsevier
Background Amyotrophic lateral sclerosis (ALS) is a progressive and often fatal
neurodegenerative disease characterized by the loss of Motor Neurons (MNs) in spinal cord …

[HTML][HTML] Antibacterial activity and wound healing potential of Cycas thouarsii R. Br n-butanol fraction in diabetic rats supported with phytochemical profiling

R Binsuwaidan, E Elekhnawy, WS Elseady… - Biomedicine & …, 2022 - Elsevier
Patients with diabetes mellitus often suffer from chronic wounds due to wound healing
impairment. Considering the increased prevalence of diabetes, this would predispose …

New insights on structures forming the lignin-like fractions of ancestral plants

J Rencoret, A Gutiérrez, G Marques… - Frontiers in Plant …, 2021 - frontiersin.org
In the present work, lignin-like fractions were isolated from several ancestral plants–
including moss (Hypnum cupressiforme and Polytrichum commune), lycophyte (Selaginella …