The changing epidemiology of autism spectrum disorders

K Lyall, L Croen, J Daniels, MD Fallin… - Annual review of …, 2017 - annualreviews.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with lifelong
impacts. Genetic and environmental factors contribute to ASD etiology, which remains …

Emerging roles for the gut microbiome in autism spectrum disorder

HE Vuong, EY Hsiao - Biological psychiatry, 2017 - Elsevier
Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that affects one
in 45 children in the United States, with a similarly striking prevalence in countries around …

[HTML][HTML] Eye tracking reveals abnormal visual preference for geometric images as an early biomarker of an autism spectrum disorder subtype associated with …

K Pierce, S Marinero, R Hazin, B McKenna… - Biological …, 2016 - Elsevier
Background Clinically and biologically, autism spectrum disorder (ASD) is heterogeneous.
Unusual patterns of visual preference as indexed by eye tracking are hallmarks; however …

Genetic epidemiology and insights into interactive genetic and environmental effects in autism spectrum disorders

YS Kim, BL Leventhal - Biological psychiatry, 2015 - Elsevier
Understanding the pathogenesis of neurodevelopmental disorders has proven to be
challenging. Using autism spectrum disorder (ASD) as a paradigmatic neurodevelopmental …

Autism biomarkers: challenges, pitfalls and possibilities

GM Anderson - Journal of Autism and Developmental Disorders, 2015 - Springer
Network perspectives, in their emphasis on components and their interactions, might afford
the best approach to the complexities of the ASD realm. Categorical approaches are unlikely …

Opposite risk patterns for autism and schizophrenia are associated with normal variation in birth size: Phenotypic support for hypothesized diametric gene-dosage …

SG Byars, SC Stearns… - Proceedings of the …, 2014 - royalsocietypublishing.org
Opposite phenotypic and behavioural traits associated with copy number variation and
disruptions to imprinted genes with parent-of-origin effects have led to the hypothesis that …

Evolutionary perspectives on polygenic selection, missing heritability, and GWAS

LH Uricchio - Human genetics, 2020 - Springer
Genome-wide association studies (GWAS) have successfully identified many trait-
associated variants, but there is still much we do not know about the genetic basis of …

The Yin and Yang of autism genetics: how rare de novo and common variations affect liability

P Chaste, K Roeder, B Devlin - Annual review of genomics and …, 2017 - annualreviews.org
The etiology of autism spectrum disorder (ASD) is complex, involving both genetic and
environmental contributions to individual and population-level liability. Early researchers …

Initial ophthalmic findings in Turkish children with autism spectrum disorder

EU Kabatas, PA Ozer, GT Ertugrul, BE Kurtul… - Journal of Autism and …, 2015 - Springer
Children with autism spectrum disorders (ASD) frequently have ophthalmologic disorders.
Due to poor cooperation with ophthalmological examination, ocular abnormalities in such …

From de novo mutations to personalized therapeutic interventions in autism

WM Brandler, J Sebat - Annual review of medicine, 2015 - annualreviews.org
The high heritability, early age at onset, and reproductive disadvantages of autism spectrum
disorders (ASDs) are consistent with an etiology composed of dominant-acting de novo …