Genetic coding variants in APOL1, which encodes apolipoprotein L1 (APOL1), were
identified in 2010 and are relatively common among individuals of sub-Saharan African …

Rates of many types of severe kidney disease are much higher in Black individuals than
most other ethnic groups. Much of this disparity can now be attributed to genetic variants in …

The growing accessibility and falling costs of genetic sequencing techniques has expanded
the utilization of genetic testing in clinical practice. For living kidney donation, genetic …

Long-term safety of living kidney donation (LKD), especially for young donors, has become a
real matter of concern in the transplant community and may contribute to creating resistance …

Despite kidney transplantation having superior outcomes to dialytic therapies, disparities
continue to exist among rates of kidney transplantation between Black and non-Hispanic …

Background. Gaps in our knowledge of long-term outcomes affect decision making for
potential living kidney donors. Methods. The Scientific Registry of Transplant Recipients was …

Background APOL1 variants contribute to the markedly higher incidence of ESKD in Blacks
compared with Whites. Genetic testing for these variants in patients with African ancestry …

Introduction While living donor (LD) kidney transplantation is the optimal treatment for
patients with kidney failure, LDs assume a higher risk of future kidney failure themselves …

A unified mechanism of pathogenesis for the various APOL1 nephropathies still remains
unclear and controversial. As ongoing studies have consistently implicated the pathogenic …

Apolipoprotein L1 (ApoL1) predictive genetic testing for kidney disease, and its emerging
role in transplantation, remains controversial as it may exacerbate underlying disparities …