[HTML][HTML] Surface-engineered nanoparticles in cancer immune response and immunotherapy: Current status and future prospects

J Chen, X Cong - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer immunotherapy is a therapeutic strategy to inhibit tumor growth and metastasis by
intervening in the immune response process. Strategies applied to cancer immunotherapy …

Biological function, regulatory mechanism, and clinical application of mannose in cancer

H Jin, X Liu, H Liu - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Studies examining the regulatory roles and clinical applications of monosaccharides other
than glucose in cancer have been neglected. Mannose, a common type of monosaccharide …

Enzyme‐Activatable Chemokine Conjugates for In Vivo Targeting of Tumor‐Associated Macrophages

ND Barth, FJ Van Dalen, U Karmakar… - Angewandte Chemie …, 2022 - Wiley Online Library
Increased levels of tumor‐associated macrophages (TAMs) are indicators of poor prognosis
in most cancers. Although antibodies and small molecules blocking the recruitment of …

Instructional materials that control cellular activity through synthetic Notch receptors

JC Lee, HJ Brien, BL Walton, ZM Eidman, S Toda… - Biomaterials, 2023 - Elsevier
The field of regenerative engineering relies primarily on the dual technical platforms of cell
selection/conditioning and biomaterial fabrication to support directed cell differentiation. As …

Mannose-coated reconstituted lipoprotein nanoparticles for the targeting of tumor-associated macrophages: optimization, characterization, and in vitro evaluation of …

AS Dossou, ME Mantsch, A Kapic, WL Burnett… - Pharmaceutics, 2023 - mdpi.com
Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as
delivery vehicles to a variety of targets, including cancer cells. However, the modification of …

Targeting Wnt/β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity

C Pundkar, F Antony, X Kang, A Mishra, RJ Babu… - Heliyon, 2023 - cell.com
The aberrant activation of Wnt/β-catenin signaling in tumor cells and immune cells in the
tumor microenvironment (TME) promotes malignant transformation, metastasis, immune …

NF-κB: Governing Macrophages in Cancer

J Cornice, D Verzella, P Arboretto, D Vecchiotti… - Genes, 2024 - mdpi.com
Tumor-associated macrophages (TAMs) are the major component of the tumor
microenvironment (TME), where they sustain tumor progression and or-tumor immunity. Due …

Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of …

AS Dossou, ME Mantsch, N Sabnis, RE Berg… - Frontiers in Drug …, 2023 - frontiersin.org
The targeting and conversion of the immunosuppressive (M2) tumor-associated
macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression …

Nanomedicine for cancer patient‐centered care

C Sorrentino, SL Ciummo, C Fieni, E Di Carlo - MedComm, 2024 - Wiley Online Library
Cancer is a leading cause of morbidity and mortality worldwide, and an increase in
incidence is estimated in the next future, due to population aging, which requires the …

Predicting the Recurrence of Gastric Cancer Using the Textural Features of Perigastric Adipose Tissue on [18F]FDG PET/CT

H Ahn, GJ Song, SH Jang, MW Son, HJ Lee… - International Journal of …, 2022 - mdpi.com
This study aimed to assess the relationship between the histopathological and textural
features of perigastric adipose tissue (AT) on 2-deoxy-2-[18F] fluoro-D-glucose ([18F] FDG) …