Outcomes of neonatal encephalopathy (NE) have improved since the widespread
implementation of therapeutic hypothermia (TH) in high-resource settings. While TH for NE …

There is no consensus on the optimal pCO2 levels in the newborn. We reviewed the effects
of hypercapnia and hypocapnia and existing carbon dioxide thresholds in neonates. A …

Background: Therapeutic hypothermia provides incomplete neuroprotection for neonatal
hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that …

With the current practice of therapeutic hypothermia for neonatal encephalopathy, disability
rates and the severity spectrum of cerebral palsy are reduced. Nevertheless, safe and …

Wide fluctuations in partial pressure of carbon dioxide (PaCO2) can potentially be
associated with neurological and lung injury in neonates. Blood gas measurement is the …

Neonatal encephalopathy is a condition of disordered neonatal brain function and is
associated with many risk factors. The incidence of neonatal encephalopathy is estimated to …

Therapeutic hypothermia (TH) has become the standard of care treatment to improve
morbidity and mortality in infants with hypoxic-ischemic encephalopathy (HIE). Although TH …

Neonates with neonatal encephalopathy (NE) often present with multi-organ dysfunction that
requires multidisciplinary specialized management. Care of the neonate with NE is thus …

Background Identification of early signs of hypoxic ischemic encephalopathy (HIE) with
magnetic resonance imaging (MRI) has proven of prognostic significance. Yet, the …

Background Cerebral autoregulation is impaired in a multitude of neurological conditions.
Increasingly, clinical studies are correlating the nature of this impairment with prognostic …