Autoimmune gastritis

MV Lenti, M Rugge, E Lahner, E Miceli… - Nature Reviews …, 2020 - nature.com
Autoimmune gastritis (AIG) is an increasingly prevalent, organ-specific, immune-mediated
disorder characterized by the destruction of gastric parietal cells, leading to the loss of …

Pernicious anemia

BH Toh, IR Van Driel, PA Gleeson - New England Journal of …, 1997 - Mass Medical Soc
Pernicious anemia is the most common cause of vitamin B12 deficiency. Vitamin B12
deficiency has many causes; the term “pernicious anemia” applies only to the condition …

Diagnosis and classification of pernicious anemia

N Bizzaro, A Antico - Autoimmunity reviews, 2014 - Elsevier
Pernicious anemia (PA) is a complex disorder consisting of hematological, gastric and
immunological alterations. Diagnosis of PA relies on histologically proven atrophic body …

Anti-parietal cell antibodies–diagnostic significance

E Rusak, A Chobot, A Krzywicka, J Wenzlau - Advances in medical …, 2016 - Elsevier
Anti-parietal cell antibodies (APCA) are an advantageous tool for screening for autoimmune
atrophic gastritis (AAG) and pernicious anemia (PA). The target for APCA is the H+/K+ ATP …

Autoimmunity and gastric cancer

N Bizzaro, A Antico, D Villalta - International Journal of Molecular …, 2018 - mdpi.com
Alterations in the immune response of patients with autoimmune diseases may predispose
to malignancies, and a link between chronic autoimmune gastritis and gastric cancer has …

Gastric autoimmunity: the role of Helicobacter pylori and molecular mimicry

MM D'Elios, BJ Appelmelk, A Amedei… - Trends in molecular …, 2004 - cell.com
Pathogens can induce autoreactive T cells to initiate autoimmune disease by several
mechanisms. Pathogen-induced inflammation results in the enhanced presentation of self …

Pernicious anemia: Pathophysiology and diagnostic difficulties

TW Htut, KZ Thein, TH Oo - Journal of Evidence‐Based …, 2021 - Wiley Online Library
Pernicious anemia (PA) is the most common cause of vitamin B12 (cobalamin) deficiency
anemia in the world. It is an autoimmune disease, comprising of salient features of …

Th1, Th2, and Th17 effector T cell-induced autoimmune gastritis differs in pathological pattern and in susceptibility to suppression by regulatory T cells

GH Stummvoll, RJ DiPaolo, EN Huter… - The Journal of …, 2008 - journals.aai.org
Th cells can be subdivided into IFN-γ-secreting Th1, IL-4/IL-5-secreting Th2, and IL-17-
secreting Th17 cells. We have evaluated the capacity of fully differentiated Th1, Th2, and …

RE. GA. IN.: the Real-world Gastritis Initiative–updating the updates

M Rugge, RM Genta, P Malfertheiner, M Dinis-Ribeiro… - Gut, 2024 - gut.bmj.com
At the end of the last century, a far-sighted 'working party'held in Sydney, Australia
addressed the clinicopathological issues related to gastric inflammatory diseases. A few …

CD4+ CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells

RJ DiPaolo, DD Glass, KE Bijwaard… - The Journal of …, 2005 - journals.aai.org
Thymic-derived, naturally occurring, CD4+ CD25+ regulatory T cells (nTreg) are potent
suppressors of immune responses. A detailed understanding of which components of the …