Over 200 million people suffer from osteoporosis worldwide. Individuals with osteoporosis
have increased rates of bone resorption while simultaneously having impaired …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Macrophage polarization refers to how macrophages have been activated at a given point in
space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate …

Rationale: Mesenchymal stem/stromal cell (MSC) therapies have shown promise in
preclinical models of pathologies relevant to newborn medicine, such as bronchopulmonary …

Persistent inflammation within the respiratory tract underlies the pathogenesis of numerous
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …

Hepatic fibrosis is a common pathological process involving persistent liver injury with
various etiologies and subsequent inflammatory responses that occur in chronic liver …

Mesenchymal stem cells (MSCs) are speculated to act at macrophage-injury interfaces to
mediate efficient repair. To explore this facet in-depth this study evaluates the influence of …

Pyruvate kinase (PK), as one of the key enzymes for glycolysis, can encode four different
subtypes from two groups of genes, although the M2 subtype PKM2 is expressed mainly …

Mitochondria are master regulators of metabolism. Mitochondria generate ATP by oxidative
phosphorylation using pyruvate (derived from glucose and glycolysis) and fatty acids (FAs) …

Dietary phenolic acids alleviate intestinal inflammation through altering gut microbiota
composition and regulating macrophage activation. However, it is unclear how individual …