A guide to artificial intelligence for cancer researchers
Artificial intelligence (AI) has been commoditized. It has evolved from a specialty resource to
a readily accessible tool for cancer researchers. AI-based tools can boost research …
a readily accessible tool for cancer researchers. AI-based tools can boost research …
Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions
Artificial intelligence (AI) in oncology is advancing beyond algorithm development to
integration into clinical practice. This review describes the current state of the field, with a …
integration into clinical practice. This review describes the current state of the field, with a …
Privacy-preserving large language models for structured medical information retrieval
Most clinical information is encoded as free text, not accessible for quantitative analysis. This
study presents an open-source pipeline using the local large language model (LLM)“Llama …
study presents an open-source pipeline using the local large language model (LLM)“Llama …
Large language model use in clinical oncology
N Carl, F Schramm, S Haggenmüller, JN Kather… - NPJ Precision …, 2024 - nature.com
Large language models (LLMs) are undergoing intensive research for various healthcare
domains. This systematic review and meta-analysis assesses current applications …
domains. This systematic review and meta-analysis assesses current applications …
From text to tables: a local privacy preserving large language model for structured information retrieval from medical documents
Abstract Background and Aims Most clinical information is encoded as text, but extracting
quantitative information from text is challenging. Large Language Models (LLMs) have …
quantitative information from text is challenging. Large Language Models (LLMs) have …
[HTML][HTML] The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S): a tool for assessing tumour-agnostic potential of molecularly guided therapies and for steering …
CB Westphalen, D Martins-Branco, JR Beal… - Annals of …, 2024 - Elsevier
Background Advances in precision oncology led to approval of tumour-agnostic molecularly
guided treatment options (MGTOs). The minimum requirements for claiming tumour-agnostic …
guided treatment options (MGTOs). The minimum requirements for claiming tumour-agnostic …
[HTML][HTML] Real-world outcomes of treatment strategy between first-line osimertinib, first/second-generation EGFR-TKIs followed by osimertinib and without osimertinib in …
Y Uehara, Y Takeyasu, T Yoshida, A Tateishi… - ESMO Real World Data …, 2024 - Elsevier
Background Osimertinib has been the standard of care in epidermal growth factor receptor
(EGFR)-mutant non-small-cell lung cancer (NSCLC). We evaluated outcomes between …
(EGFR)-mutant non-small-cell lung cancer (NSCLC). We evaluated outcomes between …
Generating and using real-world data: A worthwhile uphill battle
K Verkerk, EE Voest - Cell, 2024 - cell.com
The precision oncology paradigm challenges the feasibility and data generalizability of
traditional clinical trials. Consequently, an unmet need exists for practical approaches to test …
traditional clinical trials. Consequently, an unmet need exists for practical approaches to test …
[HTML][HTML] Atezolizumab/bevacizumab or lenvatinib in hepatocellular carcinoma: Multicenter real-world study with focus on bleeding and thromboembolic events
NB Khaled, M Möller, LS Jochheim, C Leyh, U Ehmer… - JHEP Reports, 2024 - Elsevier
Background & Aims Atezolizumab/bevacizumab (atezo/bev) and lenvatinib have
demonstrated efficacy as first-line therapies for hepatocellular carcinoma (HCC). However …
demonstrated efficacy as first-line therapies for hepatocellular carcinoma (HCC). However …
[HTML][HTML] The impact of inter-cycle treatment delays on 5-year all-cause mortality in early-stage breast cancer: A retrospective cohort study
L Steventon, E Kipps, KKC Man, R Roylance… - European Journal of …, 2024 - Elsevier
Background Inter-cycle delays to chemotherapy are often required to manage drug toxicity.
The impact of delays on mortality is poorly characterised. This retrospective cohort study …
The impact of delays on mortality is poorly characterised. This retrospective cohort study …