The evolution and clinical impact of hepatitis B virus genome diversity

PA Revill, T Tu, HJ Netter, LKW Yuen… - Nature Reviews …, 2020 - nature.com
The global burden of hepatitis B virus (HBV) is enormous, with 257 million persons
chronically infected, resulting in more than 880,000 deaths per year worldwide. HBV exists …

The hepatitis delta virus: Replication and pathogenesis

C Sureau, F Negro - Journal of hepatology, 2016 - Elsevier
Hepatitis delta virus (HDV) is a defective virus and a satellite of the hepatitis B virus (HBV).
Its RNA genome is unique among animal viruses, but it shares common features with some …

Origin, HDV genotype and persistent viremia determine outcome and treatment response in patients with chronic hepatitis delta

D Roulot, S Brichler, R Layese, Z BenAbdesselam… - Journal of …, 2020 - Elsevier
Background & Aims HDV infection causes severe chronic liver disease in individuals
infected with HBV. However, the factors associated with poor prognosis are largely …

Hepatitis delta virus

SA Hughes, H Wedemeyer, PM Harrison - The Lancet, 2011 - thelancet.com
Hepatitis delta virus (HDV) is a small, defective RNA virus that can infect only individuals
who have hepatitis B virus (HBV); worldwide more than 15 million people are co-infected …

Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors

G Fattovich, F Bortolotti, F Donato - Journal of hepatology, 2008 - Elsevier
The natural history of chronic hepatitis B virus (HBV) infection and disease is complex and
highly variable. We review the natural history of chronic hepatitis B with emphasis on the …

Diseases of the liver and biliary system.

S Sherlock - 1955 - cabidigitallibrary.org
The great increase in information on liver disease since the beginning of the second world
war made clinicians aware of the need for an authoritative review of the present position and …

[PDF][PDF] Hepatitis B virus evades innate immunity of hepatocytes but activates cytokine production by macrophages

X Cheng, Y Xia, E Serti, PD Block, M Chung… - …, 2017 - Wiley Online Library
Hepatitis B virus (HBV) infects hepatocytes specifically and causes immune‐mediated liver
damage. How HBV interacts with the innate immunity at the early phase of infection, either …

Prospective study of hepatocellular carcinoma and liver cirrhosis in asymptomatic chronic hepatitis B virus carriers

MW Yu, FC Hsu, IS Sheen, CM Chu… - American journal of …, 1997 - academic.oup.com
The authors conducted a study to assess the importance of underlying liver cirihosis in the
development of hepatocellular carcinoma (HCC) and the multifactorial etiology of liver …

[PDF][PDF] Genetic diversity and worldwide distribution of the deltavirus genus: A study of 2,152 clinical strains

F Le Gal, S Brichler, T Drugan, C Alloui, D Roulot… - …, 2017 - Wiley Online Library
Hepatitis delta virus (HDV) is responsible for the most severe form of acute and chronic viral
hepatitis. We previously proposed that the Deltavirus genus is composed of eight major …

Genotypes and viremia of hepatitis B and D viruses are associated with outcomes of chronic hepatitis D patients

CW Su, YH Huang, TI Huo, HH Shih, IJ Sheen… - Gastroenterology, 2006 - Elsevier
Background & Aims: Genotypes and viremia of hepatitis D virus (HDV) and hepatitis B virus
(HBV) may be associated with outcomes. This study evaluated the impact of viral genotypes …