Iron is an essential element that is indispensable for life. The delicate physiological body
iron balance is maintained by both systemic and cellular regulatory mechanisms. The iron …

Recently, there has been growing interest in research into the role of plant-derived
antioxidants in food and human health. The beneficial influence of many foodstuffs and …

Exosomes/small extracellular vesicles (sEVs) can serve as multifactorial mediators of cell-to-
cell communication through their miRNA and protein cargo. Quantitative proteomic analysis …

Reactive oxygen species (ROS) are an unenviable part of aerobic life. Their steady-state
concentration is a balance between production and elimination providing certain steady …

Iron is an essential mineral participating in different functions of the organism under
physiological conditions. Numerous biological processes, such as oxygen and lipid …

The heme protein myeloperoxidase (MPO) is a major constituent of neutrophils. As a key
mediator of the innate immune system, neutrophils are rapidly recruited to inflammatory …

Copper and iron are transition elements essential for life. These metals are required to
maintain the brain's biochemistry such that deficiency or excess of either copper or iron …

The central importance of iron in the pathophysiology of disease is derived from the ease
with which iron is reversibly oxidized and reduced. This property, while essential for its …

ContextMalnutrition causes death and impaired health in millions of children. Existing
interventions are effective under controlled conditions; however, little information is available …

Acute renal failure is commonly due to acute tubular necrosis (ATN), the latter representing
an acute, usually reversible loss of renal function incurred from ischemic or nephrotoxic …