Healthcare utilization is a collider: an introduction to collider bias in EHR data reuse
NG Weiskopf, DA Dorr, C Jackson… - Journal of the …, 2023 - academic.oup.com
Objectives Collider bias is a common threat to internal validity in clinical research but is
rarely mentioned in informatics education or literature. Conditioning on a collider, which is a …
rarely mentioned in informatics education or literature. Conditioning on a collider, which is a …
Electronic health records (EHRs) in clinical research and platform trials: Application of the innovative EHR-based methods developed by EU-PEARL
G Lombardo, C Couvert, M Kose, A Begum… - Journal of Biomedical …, 2023 - Elsevier
Abstract Objective Electronic Health Record (EHR) systems are digital platforms in clinical
practice used to collect patients' clinical information related to their health status and …
practice used to collect patients' clinical information related to their health status and …
[HTML][HTML] Using public clinical trial reports to probe non-experimental causal inference methods
E Steinberg, N Ignatiadis, S Yadlowsky, Y Xu… - BMC Medical Research …, 2023 - Springer
Background Non-experimental studies (also known as observational studies) are valuable
for estimating the effects of various medical interventions, but are notoriously difficult to …
for estimating the effects of various medical interventions, but are notoriously difficult to …
Sociotechnical feasibility of natural language processing-driven tools in clinical trial eligibility prescreening for Alzheimer's disease and related dementias
Background Alzheimer's disease and related dementias (ADRD) affect over 55 million
globally. Current clinical trials suffer from low recruitment rates, a challenge potentially …
globally. Current clinical trials suffer from low recruitment rates, a challenge potentially …
[HTML][HTML] Baseline representativeness of patients in clinics enrolled in the PRimary care Opioid Use Disorders treatment (PROUD) trial: comparison of trial and non-trial …
PD Wartko, H Qiu, AE Idu, O Yu, J McCormack… - BMC health services …, 2022 - Springer
Background Pragmatic primary care trials aim to test interventions in “real world” health care
settings, but clinics willing and able to participate in trials may not be representative of …
settings, but clinics willing and able to participate in trials may not be representative of …
Procurement of patient medical records from multiple health care facilities for public health research: feasibility, challenges, and lessons learned
JM McMahon, J Brasch, E Podsiadly, L Torres… - JAMIA …, 2023 - academic.oup.com
Objectives Studies that combine medical record and primary data are typically conducted in
a small number of health care facilities (HCFs) covering a limited catchment area; however …
a small number of health care facilities (HCFs) covering a limited catchment area; however …
[HTML][HTML] Impacts of Eligibility Criteria on Trial Participants' Age in Alzheimer's Disease Clinical Trials
Overly restricted and poorly designed eligibility criteria reduce the generalizability of the
results from clinical trials. We conducted a study to identify and quantify the impacts of study …
results from clinical trials. We conducted a study to identify and quantify the impacts of study …
[HTML][HTML] Clinical Research Informatics
Objectives: To summarize key contributions to current research in the field of Clinical
Research Informatics (CRI) and to select best papers published in 2021. Method: Using …
Research Informatics (CRI) and to select best papers published in 2021. Method: Using …
Evidence-Based Health Care
AE Chung, CS Evans, PJ White, E Lomotan - Clinical Informatics Study …, 2022 - Springer
Evidence-based health care is the foundation of clinical practice. Clinical informaticians
must understand the benefits and limitations of study design, assess and grade the quality of …
must understand the benefits and limitations of study design, assess and grade the quality of …
Using public clinical trial reports to evaluate observational study methods
E Steinberg, N Ignatiadis, S Yadlowsky, Y Xu… - arXiv preprint arXiv …, 2020 - arxiv.org
Observational studies are valuable for estimating the effects of various medical
interventions, but are notoriously difficult to evaluate because the methods used in …
interventions, but are notoriously difficult to evaluate because the methods used in …