Systems biology of malaria explored with nonhuman primates
MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …
generations of scientists, since its debut in 1971, and remains pertinent to the present day …
Single-cell views of the Plasmodium life cycle
E Real, L Mancio-Silva - Trends in Parasitology, 2022 - cell.com
Malaria-causing Plasmodium parasites undergo multiple phenotypic transitions as they
cycle between diverse niches in the mammalian and mosquito hosts. Recent applications of …
cycle between diverse niches in the mammalian and mosquito hosts. Recent applications of …
Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi
AO Andrade, NAC Santos, AS Bastos, JDC Pontual… - Scientific Reports, 2023 - nature.com
Obtaining Plasmodium vivax sporozoites is essential for in vitro culture of liver stage
parasites, not only to understand fundamental aspects of parasite biology, but also for drug …
parasites, not only to understand fundamental aspects of parasite biology, but also for drug …
Plasmodium berghei‐Mediated NRF2 Activation in Infected Hepatocytes Enhances Parasite Survival
A Bindschedler, J Schmuckli-Maurer… - Cellular …, 2022 - Wiley Online Library
The protozoan parasite Plasmodium, causative agent of malaria, initially invades and
develops in hepatocytes where it resides in a parasitophorous vacuole (PV). A single …
develops in hepatocytes where it resides in a parasitophorous vacuole (PV). A single …
Liver-stage fate determination in Plasmodium vivax parasites: Characterization of schizont growth and hypnozoite fating from patient isolates
Plasmodium vivax, one species of parasite causing human malaria, forms a dormant liver
stage, termed the hypnozoite, which activate weeks, months or years after the primary …
stage, termed the hypnozoite, which activate weeks, months or years after the primary …
Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi
G Mitchell, G Roma, A Voorberg-van der Wel, M Beibel… - Malaria journal, 2022 - Springer
Background The zoonotic simian parasite Plasmodium cynomolgi develops into replicating
schizonts and dormant hypnozoites during the infection of hepatocytes and is used as a …
schizonts and dormant hypnozoites during the infection of hepatocytes and is used as a …
Comparative analysis of gene expression associations between mammalian hosts and Plasmodium
P Mukherjee - 2023 - edoc.hu-berlin.de
Cross-species interactions help us understand disease mechanisms and find targets for
therapy. Gene co-expression, measured by mRNA abundance, can identify host-pathogen …
therapy. Gene co-expression, measured by mRNA abundance, can identify host-pathogen …