Intervertebral disc (IVD) degeneration is a common finding on spine imaging that increases
in prevalence with age. IVD degeneration is a frequent cause of low back pain, which is a …

More than one-third of the worldwide population is overweight or obese and therefore at risk
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …

Objectives: Intervertebral disc degeneration (IDD) is widely accepted as a cause of low back
pain and related degenerative musculoskeletal disorders. Nucleus pulposus (NP) cell …

Chronic low back pain (CLBP) is a chronic pain syndrome in the lower back region, lasting
for at least 3 months. CLBP represents the second leading cause of disability worldwide …

Intervertebral disc degeneration (IVDD) is a pathological condition that can lead to
intractable back pain or secondary neurological deficits. There is no fundamental cure for …

Excessive reactive oxygen species (ROS) generation in degenerative intervertebral disc
(IVD) indicates the contribution of oxidative stress to IVD degeneration (IDD), giving a novel …

Purpose Low back pain (LBP) is the most disabling condition worldwide. Although LBP
relates to different spinal pathologies, vertebral bone marrow lesions visualized as Modic …

Intervertebral disc (IVD) degeneration contributes largely to pathoanatomical and
degenerative changes of spinal structure that increase the risk of low back pain. Apoptosis in …

Obesity (OB) and type 2 diabetes (T2D) are among the most prevalent metabolic diseases.
They currently affect a substantial part of the world population and are characterized by …

Most chronic modern non-transmissible diseases seem to begin as the result of low-grade
inflammation extending over prolonged periods of time. The importance of diet as a source …