Pyoderma gangrenosum (PG) is a rare ulcerative skin disease that presents a therapeutic
challenge. Tumour necrosis factor alpha (TNFα) inhibitors have been reported to …

Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder characterized by
neutrophil dysfunction. There are currently no FDA-approved drugs for the treatment of this …

Primary Sjögren syndrome (SjS) is a systemic autoimmune disease that may affect 1 in 1000
people (overwhelmingly women) and that can be a serious disease with excess mortality …

Pyoderma gangrenosum (PG) is an uncommon inflammatory dermatological disorder
characterized by painful ulcers that quickly spread peripherally. The pathophysiology of PG …

The use of biologic disease modifying antirheumatic drugs (bDMARDs) in systemic
autoimmune diseases such as rheumatoid arthritis and at a lesser extent in lupus, has been …

Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders
characterized by the presence of a sterile, predominantly neutrophilic infiltrate on …

Sjogren's syndrome (SjS) is a systemic chronic autoimmune disorder characterized by
lymphocytic infiltrates in exocrine organs. Most patients present with the dryness of mouth …

Biologics are a new class of drugs which mimic the action of human proteins and interact
with circulating proteins or cellular/extracellular targets, blocking their activities. The main …

Autoimmune connective tissue diseases (CTD) include a variety of chronic autoimmune
disorders that may affect one or multiple organ systems, with the skin being frequently …

Dear Editor, Vasculitis is a group of rare diseases that cause inflammation of small, medium,
and large blood vessels. It can be primary (idiopathic) or secondary to autoimmune …