The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

For millions of years, our resident microbes have coevolved and coexisted with us in a
mostly harmonious symbiotic relationship. We are not distinct entities from our microbiome …

Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

Following a single blind, cross-over and non-randomized design we investigated the effect
of 7-day use of chlorhexidine (CHX) mouthwash on the salivary microbiome as well as …

In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Single dose administration of dietary inorganic nitrate acutely reduces blood pressure (BP)
in normotensive healthy volunteers, via bioconversion to the vasodilator nitric oxide. We …

Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …