Let's talk about sex: Differences in drug therapy in males and females
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …
man?'Perhaps unintended, such narration extends to the reality of current drug …
Ranolazine, a partial fatty acid oxidation inhibitor, its potential benefit in angina and other cardiovascular disorders
B Bhandari, L Subramanian - Recent Patents on …, 2007 - ingentaconnect.com
Chronic Angina resistant to medical treatment with hemodynamically acting agents is a
major problem in clinical setup. For such patients, large number of clinical trials have …
major problem in clinical setup. For such patients, large number of clinical trials have …
[PDF][PDF] 犬血浆中盐酸雷诺嗪LC-MS 测定及药物动力学研究
谢林， 梁艳， 刘晓东， 王广基 - 2004 - jcpu.cpu.edu.cn
目的: 建立LC-MS 法测定犬血浆中盐酸雷诺嗪浓度, 研究犬ig 和iv 盐酸雷诺嗪后的药物动力学.
方法: 取血浆20 μl, 加乙腈300 μl 沉淀蛋白, 离心后10 μl 直接进样. 色谱柱为Shim-pack ODS 5 …
方法: 取血浆20 μl, 加乙腈300 μl 沉淀蛋白, 离心后10 μl 直接进样. 色谱柱为Shim-pack ODS 5 …
Gender difference regarding schizandrin pharmacokinetics in rats
MJ Xu, GJ Wang, HT Xie, H Li, Q Huang… - European journal of …, 2008 - Springer
The difference in the pharmacokinetics of schizandrin (SZ) in male and female rats was
studied. SZ concentrations in the plasma were detennined after the intragastric (ig) …
studied. SZ concentrations in the plasma were detennined after the intragastric (ig) …
[PDF][PDF] 盐酸雷诺嗪在大鼠肝微粒体内代谢的性别差异
钟皎， 柳晓泉， 陈燕， 赵小平， 王永升， 王广基 - 2006 - jcpu.cpu.edu.cn
摘要目的: 用大鼠肝微粒体研究盐酸雷诺嗪代谢的性别差异及选择性CYP
抑制剂对其代谢的影响. 方法: 盐酸雷诺嗪分别与雌性或雄性大鼠的肝微粒体温孵 …
抑制剂对其代谢的影响. 方法: 盐酸雷诺嗪分别与雌性或雄性大鼠的肝微粒体温孵 …
Tolerability and pharmacokinetics of ranolazine following single and multiple sustained-release doses in Chinese healthy adult volunteers: a randomized, open-label …
QY Tan, HD Li, RH Zhu, QZ Zhang, J Zhang… - American Journal of …, 2013 - Springer
Abstract Background and Objectives Ranolazine was approved by the US Food and Drug
Administration in January 2006 for the treatment of chronic angina pectoris, and is the first …
Administration in January 2006 for the treatment of chronic angina pectoris, and is the first …
Gender differences in limonin pharmacokinetics in rats
In the present study, the pharmacokinetics of limonin (LM) were investigated in male and
female rats. LM concentrations in the plasma were determined after the oral administration …
female rats. LM concentrations in the plasma were determined after the oral administration …
大鼠口服尼莫地平吸收动力学性别差异研究
王晓莉， 谢林， 刘晓东 - 中国临床药理学与治疗学, 2004 - manu41.magtech.com.cn
目的研究大鼠ig 尼莫地平(NMD) 后体内药物动力学是否存在性别差异, 并考察合用红霉素(Ery)
后血浆中NMD 变化. 方法雌性和雄性大鼠单独ig NMD 或与Ery 合用后, 用HPLC …
后血浆中NMD 变化. 方法雌性和雄性大鼠单独ig NMD 或与Ery 合用后, 用HPLC …
Long-term nerve excitability changes by persistent Na+ current blocker ranolazine
H Nodera, SB Rutkove - Neuroscience letters, 2012 - Elsevier
The persistent Na+ current (Nap) in peripheral axons plays an important functional role in
controlling the axonal excitability. Abnormal Nap is believed to contribute to …
controlling the axonal excitability. Abnormal Nap is believed to contribute to …
Ranolazinein dunning modeli sıçan prostat kanseri üzerindeki rolü: Primer tümör ve metastazlar
Z Karagöz - 2015 - acikbilim.yok.gov.tr
Prostat kanseri, özellikle elli yaşın üzerindeki erkeklerde yaygın olarak görülen kanserlerden
biridir. Prostat kanserinin tedavisi için çeşitli yöntemler bulunmakla birlikte, hastalığın …
biridir. Prostat kanserinin tedavisi için çeşitli yöntemler bulunmakla birlikte, hastalığın …