Surface-initiated polymer brushes in the biomedical field: applications in membrane science, biosensing, cell culture, regenerative medicine and antibacterial coatings

M Krishnamoorthy, S Hakobyan, M Ramstedt… - Chemical …, 2014 - ACS Publications
Understanding and controlling interfaces has proven to be key to a very wide range of
applications, from optical and electronic materials 1, 2 to energy storage and production, 3 …

Bioapplications of RAFT polymerization

C Boyer, V Bulmus, TP Davis, V Ladmiral, J Liu… - Chemical …, 2009 - ACS Publications
A living radical polymerization (LRP) is a free radical polymerization that aims at displaying
living character,(ie, does not terminate or transfer and is able to continue polymerization …

Living radical polymerization by the RAFT process–a second update

G Moad, E Rizzardo, SH Thang - Australian journal of chemistry, 2009 - CSIRO Publishing
This paper provides a second update to the review of reversible deactivation radical
polymerization achieved with thiocarbonylthio compounds (ZC (= S) SR) by a mechanism of …

Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications

Y Liang, KL Kiick - Acta biomaterialia, 2014 - Elsevier
Heparin plays an important role in many biological processes via its interaction with various
proteins, and hydrogels and nanoparticles comprising heparin exhibit attractive properties …

Sulfated polysaccharide directs therapeutic angiogenesis via endogenous VEGF secretion of macrophages

Y Yu, K Dai, Z Gao, W Tang, T Shen, Y Yuan… - Science …, 2021 - science.org
Notwithstanding the remarkable progress in the clinical treatment of ischemic disease,
proangiogenic drugs mostly suffer from their abnormal angiogenesis and potential cancer …

Incorporation of heparin into biomaterials

SE Sakiyama-Elbert - Acta biomaterialia, 2014 - Elsevier
This review provides an overview of the incorporation of heparin into biomaterials with a
focus on drug delivery and the use of heparin-based biomaterials for self-assembly of …

Heparin-mimicking polymers: synthesis and biological applications

SJ Paluck, TH Nguyen, HD Maynard - Biomacromolecules, 2016 - ACS Publications
Heparin is a naturally occurring, highly sulfated polysaccharide that plays a critical role in a
range of different biological processes. Therapeutically, it is mostly commonly used as an …

Heparin-based and heparin-inspired hydrogels: size-effect, gelation and biomedical applications

C He, H Ji, Y Qian, Q Wang, X Liu, W Zhao… - Journal of Materials …, 2019 - pubs.rsc.org
Heparin is the highest negatively charged biomolecule, which is a polysaccharide belonging
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …

A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor

TH Nguyen, SH Kim, CG Decker, DY Wong, JA Loo… - Nature …, 2013 - nature.com
Basic fibroblast growth factor (bFGF) is a protein that plays a crucial role in diverse cellular
functions, from wound healing to bone regeneration. However, a major obstacle to the …

A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165)

H Koide, K Yoshimatsu, Y Hoshino, SH Lee… - Nature …, 2017 - nature.com
Protein affinity reagents are widely used in basic research, diagnostics and separations and
for clinical applications, the most common of which are antibodies. However, they often …