Objective To provide an objective basis for evaluating the risk-benefit ratio of long-term
androgen use in patients with hereditary angioedema (HAE). Data Sources PubMed was …

Advances in understanding the pathophysiology and mechanism of swelling in hereditary
angioedema (HAE) has resulted in the development of multiple new drugs for the acute and …

Consensus guidelines recommend plasma-derived C1 inhibitor (C1-INH) as first-line
treatment in pregnant women with hereditary angioedema (HAE). We conducted a …

C1-inhibitor (C1-INH) deficiency is the genetic defect underlying hereditary angioedema
(HAE). Subjects with HAE suffer from recurrent angioedema that may result in death when it …

Backgroud. Hereditary angioedema (HAE) is characterized by recurrent swelling of the skin,
the abdomen (causing severe acute pain), and the airways. A recently discovered type …

Backgroud Hereditary angioedema (HAE) is a rare genetic disorder caused by a deficiency
of the plasma protein C1 inhibitor (C1-INH). HAE is characterised by the onset of …

Discussion Hereditary angioedema is an autosomal-dominant disease produced by a
deficiency of functioning C1-INH. The C1-INH is a plasma protease that functions to block …

Hereditary angioedema is a potentially life-threatening condition which can complicate
pregnancy. A 34-year-old patient with known C1 esterase inhibitor (C1INH) deficiency was …

Despite remarkable progress in understanding the molecular basis of C1 inhibitor (C1INH)
deficiency (see article by Wagenaar-Bos and Hack elsewhere in this issue) and the …

Background: While there is no approved effective therapy for the treatment of acute attacks
of hereditary angioedema in the USA, four different drugs are completing or have recently …