Understanding organotropism in cancer metastasis using microphysiological systems

J Ko, J Song, Y Lee, N Choi, HN Kim - Lab on a Chip, 2024 - pubs.rsc.org
Cancer metastasis, the leading cause of cancer-related deaths, remains a complex
challenge in medical science. Stephen Paget's “seed and soil theory” introduced the …

SMILE platform: an innovative microfluidic approach for on-chip sample manipulation and analysis in oral cancer diagnosis

S Zoupanou, A Volpe, E Primiceri, C Gaudiuso… - Micromachines, 2021 - mdpi.com
Oral cancer belongs to the group of head and neck cancers, and, despite its large diffusion,
it suffers from low consideration in terms of prevention and early diagnosis. The main …

Microfluidic device using metallic nanostructure arrays for the isolation, detection, and purification of exosomes

YS Hsiao, CW Chen, R Haliq, PM Yiu, PI Wu… - Journal of Alloys and …, 2023 - Elsevier
Microfluidic devices are widely used in disease detection and specimen separation due to
their low cost, rapid processing, and the ability to use even minuscule samples. This study …

A novel dual-function SERS-based identification strategy for preliminary screening and accurate diagnosis of circulating tumor cells

D Zhang, J Lin, Y Xu, X Wu, X Xu, Y Xie… - Journal of Materials …, 2023 - pubs.rsc.org
Non-specific adsorption of bioprobes based on surface-enhanced Raman spectroscopy
(SERS) technology inevitably endows white blood cells (WBC) in the peripheral blood with …

Rapid electrochemical-biosensor microchip platform for determination of microalbuminuria in CKD patients

CC Tseng, CH Ko, SY Lu, CE Yang, LM Fu, CY Li - Analytica Chimica Acta, 2021 - Elsevier
An electrochemical-biosensor (EC-biosensor) microchip consisting of screen-printed
electrodes and a double-layer reagent paper detection zone impregnated with amaranth is …

[HTML][HTML] The combination of computed tomography features and circulating tumor cells increases the surgical prediction of visceral pleural invasion in clinical T1N0M0 …

J Shi, F Li, F Yang, Z Dong, Y Jiang… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background Visceral pleural invasion (VPI) is a clinical manifestation associated with a poor
prognosis, and diagnosing it preoperatively is highly imperative for successful sublobar …

Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells

N Shimmyo, M Furuhata, M Yamada, R Utoh, M Seki - Analyst, 2022 - pubs.rsc.org
Numerous attempts have been made to develop efficient systems to purify trace amounts of
circulating tumor cells (CTCs) from blood samples. However, current technologies are …

Hydrodynamic cell capture in microfluidic devices

H Summala - 2023 - trepo.tuni.fi
In recent years, utilizing microfluidic devices in vitro cell interaction studies has gained
popularity among biomedical engineering field. Potential of such devices in for instance …

Novel Dual-Function Sers Identification Strategy for Preliminary Screening and Accurate Diagnosis of Circulating Tumor Cells

A Wu, D Zhang, J Lin, Y Xu, X Wu, X Xu, Y Xie, T Pan… - papers.ssrn.com
Surface-enhanced Raman spectroscopy (SERS) technology served as bioprobes holds
great promise for the detection of circulating tumor cells (CTCs). However, the non-specific …