Cofilin is an actin-binding protein that regulates filament dynamics and depolymerization.
The over-expression of cofilin is observed in various cancers, cofilin promotes cancer …

Erectile dysfunction (ED) is an important cause of reduced quality of life for men and their
partners. Recent studies have found that cavernous nerve injury (CNI) during prostate …

Background Arnidiol is a pentacyclic triterpene diol that has multiple pharmacological
activities. However, the apoptotic activities of arnidiol in human cancer cells have not yet …

Introduction: Erectile dysfunction (ED) is a common complication after radical prostatectomy
(RP), and it seriously affects the quality of life in patients and their partners. The primary …

Background Erectile dysfunction (ED) caused by intraoperative nerve injury is a major
complication of pelvic surgery. Adipose-derived stem cells (ADSCs) have presented …

Neurogenic erectile dysfunction (nED) is one of the most common and intractable
postoperative complications of rectal and prostate cancer surgery and sometimes …

Background Radical prostatectomy (RP) and radiation treatment are standard options for
localized prostate cancer. Even though nerve‐sparing techniques have been increasingly …

Introduction Cavernosal fibrosis is an important pathologic condition leading to erectile
dysfunction (ED). The etiologies of cavernosal fibrosis include aging, diabetes mellitus …

Background Erectile dysfunction (ED) often occurs due to cavernous nerve injury (CNI) after
colorectal surgery. Cell-based therapies have great potential for the treatment of CNI-related …

The LIM kinases (LIMK1 and LIMK2), known as downstream effectors, and the Rho-
associated protein kinase (ROCK), a regulator of actin dynamics, have effects on a diverse …