Understanding and interpreting antinuclear antibody tests in systemic rheumatic diseases

X Bossuyt, E De Langhe, MO Borghi… - Nature Reviews …, 2020 - nature.com
Antinuclear antibodies (ANAs) are valuable laboratory markers to screen for and support the
diagnosis of various rheumatic diseases (known as ANA-associated rheumatic diseases) …

The past, present, and future in antinuclear antibodies (ANA)

J Irure-Ventura, M López-Hoyos - Diagnostics, 2022 - mdpi.com
Autoantibodies are a hallmark of autoimmunity and, specifically, antinuclear antibodies
(ANAs) are the most relevant autoantibodies present in systemic autoimmune rheumatic …

Understanding the value of non-specific abnormal capillary dilations in presence of Raynaud's phenomenon: a detailed capillaroscopic analysis

G Pacini, A Pogna, M Pendolino, C Pizzorni… - RMD open, 2022 - rmdopen.bmj.com
Background Nailfold videocapillaroscopy (NVC) non-specific abnormalities may be present
in subjects with isolated Raynaud's phenomenon (RP) before the potential transition to …

Peripheral levels of brain-derived neurotrophic factor and S100B in neuropsychiatric systemic lupus erythematous

E Noris-García, S Arce, P Nardin, ME Lanigan… - Lupus, 2018 - journals.sagepub.com
Background The aim of this study was to investigate serum S100B and brain-derived
neurotrophic factor (BDNF) in systemic lupus erythematous (SLE) patients, with and without …

Clinical utility of ANA-ELISA vs ANA-immunofluorescence in connective tissue diseases

OS Alsaed, LI Alamlih, O Al-Radideh, P Chandra… - Scientific Reports, 2021 - nature.com
We investigated the performance of ANA-ELISA for CTDs screening and diagnosis and
comparing it to the conventional ANA-IIF. ANA-ELISA is a solid-phase immune assay …

Serological abnormalities that predict progression to systemic autoimmune rheumatic diseases in antinuclear antibody–positive individuals

C Muñoz-Grajales, SD Prokopec, SR Johnson… - …, 2022 - academic.oup.com
Objective We investigated the autoantibody (autoAb) profiles in ANA+ individuals lacking
systemic autoimmune rheumatic disease (SARD) and early SARD patients to determine the …

Relationships among antibodies against extractable nuclear antigens, antinuclear antibodies, and autoimmune diseases in a Brazilian public hospital

FW Banhuk, BC Pahim, AS Jorge… - Autoimmune …, 2018 - Wiley Online Library
One characteristic of autoimmune diseases (ADs) is the production of autoantibodies for
extractable nuclear autoantigens, which may aid in the discrimination of the different types of …

Lower urinary tract symptoms in systemic sclerosis: a detailed investigation

G Pacini, S Paolino, A C. Trombetta, F Goegan… - …, 2020 - academic.oup.com
Objectives Urinary tract involvement is a seldom-reported manifestation of SSc that could
compromise patients' quality of life. This study compares lower urinary tract symptoms …

Clinical consequences of the presence of anti-RNA Pol III antibodies in systemic sclerosis

E Wielosz, M Dryglewska, M Majdan - Advances in Dermatology and …, 2020 - termedia.pl
Clinical consequences of the presence of anti-RNA Pol III antibodies in systemic sclerosis
Page 1 Advances in Dermatology and Allergology 6, December/2020 909 This is an Open …

Challenges and advances in SLE autoantibody detection and interpretation

MY Choi, MJ Fritzler - Current Treatment Options in Rheumatology, 2019 - Springer
Purpose of review This review is an overview of key autoantibodies used in the diagnosis
and management of SLE. Questions addressed are the advantages to but limitations of ANA …