The role of serotonin (5-hydroxytryptamine; 5-HT) in the treatment of depressive and anxiety
disorders is underscored by the therapeutic action of selective 5-HT reuptake inhibitors …

The existence of an endogenous vasoconstrictor in blood serum (Stevens and Lee, 1984;
Brodie, 1900) and the presence in the gut of a substance that increases intestinal motility …

Previous reviews have well illustrated how antidepressant treatments can differentially alter
several neurotransmitter systems in various brain areas. This review focuses on the effects …

There is considerable interest in the regulation of the extracellular compartment of the
transmitter serotonin (5-hydroxytryptamine, 5-HT) in the midbrain raphe nuclei because it …

A very important element controlling serotonin (5‐HT) release throughout the brain is the 5‐
HT1A autoreceptor present on the soma and dendrites of 5‐HT neurons since it exerts a …

During the last decade, serotonin (5-HT) 1A receptors have been a major target for
neurobiological research and drug development. 5-HT 1A receptors have been cloned and …

The effects of manipulating 5-hydroxytryptamine (5HT) neuronal function in humans and in
animals are reviewed. 5HT pathways do not have a unitary function in modulating anxiety. It …

Electrophysiological and autoradiographic approaches were used to assess possible
changes in 5-hydroxytryptamine (serotonin) 5-HT 1A receptors in the rat dorsal raphe …

The present study was undertaken to compare the acute and long-term effects of
escitalopram and citalopram on rat brain 5-HT neurotransmission, using …

Adaptive changes in the serotonergic system are generally believed to underlie the
therapeutic effectiveness of the azapirone anxiolytics and a variety of antidepressant drugs …