The etiology of nerve cell death in neuronal degenerative diseases is unknown, but it has
been hypothesized that excitotoxic mechanisms may play a role. Such mechanisms may …

Knowledge of the effect of dopamine on corticostriatal synaptic plasticity has advanced
rapidly over the last 5 years. We consider this new knowledge in relation to three factors …

The anatomical distributions and affinity states of dopamine D 1 and D 2 receptors were
compared in the rat central nervous system using quantitative autoradiography.[3 H] …

The involvement of dopamine (DA) in drug reinforcement is well established, but much less
in known about its contribution to addiction. We have used positron emission tomography to …

Synaptic release of dopamine in the nucleus accumbens of the intact rat brain elicited by a
single electrical impulse applied to ascending dopaminergic fibers results in extracellular …

The precise localization of D1 and D2 dopamine receptors within striatal neurons and
circuits is crucial information for further understanding dopamine pharmacology. We have …

The effect of posttraining intracerebral injections of the indirect dopamine (DA) agonist d-
amphetamine, the direct D2 agonist LY 171555, and the direct D1 agonist SKF-38393 on the …

Several lines of evidence suggest the existence of multiple dopamine receptor subtypes,
referred to as D1 and D2. The present study examines the distribution of these dopamine …

The nucleus accumbens septi (Acb) represents an interface between limbic and motor
systems and a site for modulation of these integrative functions by ascending …

The cerebral cortex and the intralaminar thalamic nuclei are the major sources of excitatory
glutamatergic afferents to the striatum, whereas the midbrain catecholaminergic neurones …