Non-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significance

C Huang, P Azizi, M Vazirzadeh… - Journal of Translational …, 2023 - Springer
Cancer is a complex disease with many contributing factors, and researchers have gained
extensive knowledge that has helped them understand the diverse and varied nature of …

A systematic review of miR-29 in cancer

JJ Kwon, TD Factora, S Dey, J Kota - Molecular Therapy-Oncolytics, 2019 - cell.com
MicroRNAs (miRNA) are small non-coding RNAs (∼ 22 nt in length) that are known as
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …

[HTML][HTML] Pancreatic stellate cell: Pandora's box for pancreatic disease biology

RR Bynigeri, A Jakkampudi, R Jangala… - World journal of …, 2017 - ncbi.nlm.nih.gov
Pancreatic stellate cells (PSCs) were identified in the early 1980s, but received much
attention after 1998 when the methods to isolate and culture them from murine and human …

miRNA: a diagnostic and therapeutic tool for pancreatic cancer

MI Qadir, A Faheem - Critical Reviews™ in Eukaryotic Gene …, 2017 - dl.begellhouse.com
Pancreatic ductal adenocarcinoma (PDAC) is fatal disease and one of the major causes of
death among cancer patients. Diagnosis of PDAC during the early stages of cancer using …

The role of miR‐29 family in disease

M Horita, C Farquharson… - Journal of cellular …, 2021 - Wiley Online Library
MicroRNAs are small noncoding RNAs that can bind to the target sites in the 3'‐untranslated
region of messenger RNA to regulate posttranscriptional gene expression. Increasing …

Pancreatic cancer: Stroma and its current and emerging targeted therapies

J Kota, J Hancock, J Kwon, M Korc - Cancer letters, 2017 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human malignancies
with a 5-year survival rate of 8%. Dense, fibrotic stroma associated with pancreatic tumors is …

The role of stellate cells in pancreatic ductal adenocarcinoma: targeting perspectives

Y Wu, C Zhang, K Jiang, J Werner, AV Bazhin… - Frontiers in …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is a gastrointestinal malignancy with a dismal
clinical outcome. Accumulating evidence suggests that activated pancreatic stellate cells …

Role of non-coding RNAs in tumor progression and metastasis in pancreatic cancer

LF Sempere, K Powell, J Rana, AA Brock… - Cancer and Metastasis …, 2021 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer with an
overall 5-year survival rate of less than 10%. The 1-year survival rate of patients with locally …

MiRNA-203 suppresses cell proliferation, migration and invasion in colorectal cancer via targeting of EIF5A2

B Deng, B Wang, J Fang, X Zhu, Z Cao, Q Lin, L Zhou… - Scientific reports, 2016 - nature.com
While it is known that miR-203 is frequently downregulated in many types of human cancer,
little is known regarding its expression and functional role in colorectal cancer (CRC). In this …

Effects of TP53 mutations and miRs on immune responses in the tumor microenvironment important in pancreatic cancer progression

JA McCubrey, LV Yang, SL Abrams, LS Steelman… - Cells, 2022 - mdpi.com
Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC).
PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are …