This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

Updating the classification of hematologic neoplasia with germline predisposition, pediatric
myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML) is critical …

The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …

The NCCN Guidelines for Myelodysplastic Syndromes (MDS) provide recommendations for
the evaluation, diagnosis, and management of patients with MDS based on a review of …

Fanconi anemia (FA) patients experience chromosome instability, yielding hematopoietic
stem/progenitor cell (HSPC) exhaustion and predisposition to poor-prognosis myeloid …

Background Early recognition of xeroderma pigmentosum is important to minimize the
complications arising from the harmful effects of exposure to ultraviolet radiation. This …

DNA damage response is essential to human physiology. A broad spectrum of pathologies
are displayed by individuals carrying monoallelic or biallelic loss-of-function mutations in …

Base and nucleotide excision repair (BER and NER) pathways are normally associated with
removal of specific types of DNA damage: small base modifications (such as those induced …

Network embedding approaches are gaining momentum to analyse a large variety of
networks. Indeed, these approaches have demonstrated their effectiveness in tasks such as …

Xeroderma pigmentosum (XP) is characterized by: Acute sun sensitivity (severe sunburn
with blistering, persistent erythema on minimal sun exposure) with marked freckle-like …